Frequency of Thyroid Carcinoma in Brazilian TP53 p.R337H Carriers With Li Fraumeni Syndrome
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2016.6389
Abstract: Importance Li Fraumeni syndrome (LFS) is associated with a wide variety of tumors; nevertheless, thyroid carcinoma has not been evaluated in this syndrome. Due to the Brazilian founder mutation p.R337H, some tumors that have not… read more here.
Keywords: thyroid carcinoma; tp53 r337h; mutation;
Overexpression of the pro-protein convertase furin predicts prognosis and promotes papillary thyroid carcinoma progression and metastasis through RAF/MEK signaling.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular oncology"
DOI: 10.1002/1878-0261.13396
Abstract: Furin belongs to the pro-protein convertases (PCs) family and its aberrant expression has been documented in various types of cancers; however, its role in thyroid cancer remains unclear. We investigated the expression of furin in… read more here.
Keywords: thyroid carcinoma; furin; ptc; braf ... See more keywords
Spatial Transcriptomics Reveals Transcriptomic and Immune Microenvironment Reprogramming during Thyroid Carcinoma Dedifferentiation
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202506925
Abstract: Anaplastic thyroid carcinoma (ATC) is one of the most lethal human malignancies, often evolving from differentiated thyroid carcinoma (DTC) through a poorly understood dedifferentiation process. To elucidate this transition, spatial transcriptomic sequencing (spRNAseq) is performed… read more here.
Keywords: carcinoma; thyroid carcinoma; atc regions; immune microenvironment ... See more keywords
Identification and Validation of Prognostic Signature of Papillary Thyroid Carcinoma Based on Six Immune-Related lncRNAs.
Sign Up to like & getrecommendations! Published in 2025 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.70063
Abstract: This research seeks to identify and verify the prognostic signature of immune-related RNA of papillary thyroid carcinoma (PTC). The Cancer Genome Atlas (TCGA) database provided the PTC samples and clinical data. Using the limma program,… read more here.
Keywords: ptc; signature; thyroid carcinoma; immune related ... See more keywords
Prognostic significance of gross extrathyroidal extension invading only strap muscles in differentiated thyroid carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Surgery"
DOI: 10.1002/bjs.10830
Abstract: In the eighth edition of the AJCC staging system for differentiated thyroid carcinoma (DTC), minimal extrathyroidal extension (ETE) is no longer a determinant of T3 category. Instead, gross ETE invading only strap muscles has been… read more here.
Keywords: extrathyroidal extension; invading strap; differentiated thyroid; strap muscles ... See more keywords
The association of obesity with thyroid carcinoma risk
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4498
Abstract: The prevalence of obesity and an increased incidence of thyroid carcinoma (TC) threaten public health in parallel on a global scale. Sufficient evidence supports excess body fatness in thyroid carcinogenesis, and the role and anthropometric… read more here.
Keywords: association obesity; thyroid carcinoma; obesity thyroid; risk ... See more keywords
Response to neoadjuvant paclitaxel predicts survival in anaplastic thyroid carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5219
Abstract: The clinical utilities of paclitaxel in anaplastic thyroid carcinoma (ATC) have been reported. The current study investigated the outcomes in ATC patients treated by paclitaxel as neoadjuvant setting. Furthermore, the prognostic factor for overall survival… read more here.
Keywords: thyroid carcinoma; response paclitaxel; paclitaxel; response ... See more keywords
RNF150 suppresses thyroid carcinoma by inactivating the p38 pathway via ubiquitination of ASK1.
Sign Up to like & getrecommendations! Published in 2022 at "Cell biology international"
DOI: 10.1002/cbin.11786
Abstract: Thyroid carcinoma (THCA) is the most prevalent cancer in endocrine system. However, the pathogenic mechanism underlying tumor recurrence remains unclear. RING finger protein (RNF) family plays a crucial role in cancers whereas the role of… read more here.
Keywords: inactivating p38; thyroid carcinoma; rnf150; rnf150 thca ... See more keywords
Concordance in postsurgical radioactive iodine therapy recommendations between Watson for Oncology and clinical practice in patients with differentiated thyroid carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Cancer"
DOI: 10.1002/cncr.32166
Abstract: To the authors' knowledge, the indications for radioactive iodine (RAI) therapy in patients with differentiated thyroid carcinoma (DTC) are unclear; treatment decisions are based on physician judgment. The objective of the current study was to… read more here.
Keywords: patients differentiated; radioactive iodine; differentiated thyroid; thyroid carcinoma ... See more keywords
Building on recent cytomorphologic descriptions of NTRK‐rearranged thyroid carcinoma
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DOI: 10.1002/cncy.22413
Abstract: Although neurotrophin tyrosine receptor kinase (NTRK)– rearranged thyroid carcinoma (NRTC) is uncommon, its possible aggressive behavior and the availability of targeted therapies make its recognition relevant. We read with interest the first cytomorphologic characterizations of… read more here.
Keywords: building recent; ntrk rearranged; rearranged thyroid; thyroid carcinoma ... See more keywords
Development and validation of an RNA sequencing–based classifier for medullary thyroid carcinoma on thyroid FNA
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Cytopathology"
DOI: 10.1002/cncy.22643
Abstract: Medullary thyroid carcinoma (MTC) is an uncommon malignancy of C- cell origin that accounts for < 3% of all thyroid cancers. 1,2 However, the prognosis for MTC, which is derived from parafollicular C cells, has… read more here.
Keywords: thyroid carcinoma; mtc; thyroid; validation ... See more keywords