Maternal Thyroid Hormone Replacement Therapy Exposure and Language and Communication Skills of Offspring at 8 Years of Age
Sign Up to like & getrecommendations! Published in 2019 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2019.12424
Abstract: Key Points Question Is prenatal exposure to thyroid hormone replacement therapy associated with children’s language, speech, and communication skills at 8 years of age? Findings In this nationwide population-based cohort linkage study of 53 862 mother-child… read more here.
Keywords: replacement therapy; thyroid hormone; hormone replacement;
Thyroid Hormone Deficiency Disrupts Embryonic Ventral Body Wall Development and Myogenesis With Partial Recovery Following LevothyroxineTherapy
Sign Up to like & getrecommendations! Published in 2025 at "Birth Defects Research"
DOI: 10.1002/bdr2.2520
Abstract: Ventral body wall defects (VBWDs), including omphalocele and gastroschisis, result from failed embryonic midline closure and contribute to high neonatal morbidity. While thyroid hormones (THs) are essential for morphogenesis, their role in VBWD pathogenesis is… read more here.
Keywords: body wall; hormone deficiency; thyroid hormone; ventral body ... See more keywords
The Role of Thyroid Hormone in Neuronal Protection.
Sign Up to like & getrecommendations! Published in 2021 at "Comprehensive Physiology"
DOI: 10.1002/cphy.c200019
Abstract: Thyroid hormone is essential for brain development and brain function in the adult. During development, thyroid hormone acts in a spatial and temporal-specific manner to regulate the expression of genes essential for normal neural cell… read more here.
Keywords: hormone; role; function; brain ... See more keywords
Development of a Zebrafish Embryo-Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research.
Sign Up to like & getrecommendations! Published in 2024 at "Environmental toxicology and chemistry"
DOI: 10.1002/etc.5878
Abstract: There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system-disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co-operation… read more here.
Keywords: system; chemistry; thyroid hormone; hormone system ... See more keywords
Oligodendrocyte progenitor cell maturation is dependent on dual function of MCT8 in the transport of thyroid hormone across brain barriers and the plasma membrane
Sign Up to like & getrecommendations! Published in 2021 at "Glia"
DOI: 10.1002/glia.24014
Abstract: Inactivating mutations in the thyroid hormone (TH) transporter monocarboxylate transporter 8 (MCT8) causes a rare and debilitating form of X‐linked psychomotor disability known as Allan Herndon Dudley syndrome (AHDS). One of the most prominent pathophysiological… read more here.
Keywords: mct8; across brain; oligodendrocyte progenitor; maturation ... See more keywords
Thyroid Hormone Signaling and the Liver
Sign Up to like & getrecommendations! Published in 2020 at "Hepatology"
DOI: 10.1002/hep.31296
Abstract: Thyroid hormone (TH) plays a critical role in maintaining metabolic homeostasis throughout life. It is well known that the liver and thyroid are intimately linked, with TH playing important roles in de novo lipogenesis, beta‐oxidation… read more here.
Keywords: hormone; hormone signaling; signaling liver; liver thyroid ... See more keywords
Altered thyroid hormone levels affect body condition at metamorphosis in larvae of Xenopus laevis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3663
Abstract: Chemical, physical and biological environmental stressors may affect the endocrine system, such as the thyroid hormone (TH) axis in larval amphibians with consequences for energy partitioning among development, growth and metabolism. We studied the effects… read more here.
Keywords: xenopus laevis; development; thyroid hormone; body condition ... See more keywords
Effect of thyroid hormone‐disrupting chemicals on swim bladder inflation and thyroid hormone‐related gene expression in Japanese medaka and zebrafish
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4302
Abstract: We compared the influence of thyroid hormone‐disrupting chemicals (heptafluorobutanoic acid, PFBA and tris[1,3‐dichloro‐2‐propyl] phosphate, TDCPP) and thyroid hormone (3,3′,5‐triiodo‐L‐thyronine, T3) on swim bladder inflation and thyroid hormone‐related gene expression in Japanese medaka and zebrafish. The… read more here.
Keywords: bladder inflation; hormone; swim bladder; thyroid hormone ... See more keywords
2,3′,4,4′,5‐Pentachlorobiphenyl attenuated fast‐twitch fibers and fiber size of skeletal muscle via disturbing thyroid hormone signaling and mitochondrial dynamics
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4330
Abstract: Polychlorinated biphenyls (PCBs) affect multiple organs, and some of the effects are mediated by interfering with thyroid hormone (TH) signaling that regulates physiological processes in mammals. It remains unclear how PCBs affect skeletal muscle (SM).… read more here.
Keywords: hormone signaling; muscle; pcb118; thyroid hormone ... See more keywords
Association between thyroid hormone resistance and obesity: a cross‐sectional study and mouse stimulation test
Sign Up to like & getrecommendations! Published in 2024 at "Obesity"
DOI: 10.1002/oby.24084
Abstract: Thyroid hormone influences key metabolic pathways, and reduced sensitivity to thyroid hormone is considered a new risk factor for adverse metabolic outcomes. However, the association between thyroid hormone resistance and obesity in euthyroid individuals is… read more here.
Keywords: association thyroid; thyroid hormone; hormone resistance; hormone ... See more keywords
Thyroid Hormone Action: The p43 Mitochondrial Pathway.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7902-8_14
Abstract: The possibility that several pathways are involved in the multiplicity of thyroid hormone physiological influences led to searches for the occurrence of T3 extra nuclear receptors. The existence of a direct T3 mitochondrial pathway is… read more here.
Keywords: mitochondrial pathway; pathway; hormone action; thyroid hormone ... See more keywords