Articles with "thyroid modality" as a keyword



A proposal of criteria to support the EU classification on endocrine disruption for the thyroid modality and their application to four data-rich case studies

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Published in 2025 at "Archives of Toxicology"

DOI: 10.1007/s00204-025-04037-9

Abstract: Recently, the European Commission has implemented hazard categories to classify substances as endocrine disruptors for human health, i.e. ED HH 1 or ED HH 2, depending on the weight-of-evidence. However, specific guidance on how to… read more here.

Keywords: classification; proposal; thyroid modality; case studies ... See more keywords

Amphibian studies to investigate the endocrine-disrupting properties of chemicals through the thyroid modality: a comparison of their statistical power

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Published in 2025 at "Environmental Toxicology and Chemistry"

DOI: 10.1093/etojnl/vgaf067

Abstract: Abstract Amphibians are the current model species for investigating the endocrine-disrupting (ED) properties through the thyroid modality in non-mammalian species. A recurrent question in the European Union (EU) regulatory endocrine assessment of pesticide active substances… read more here.

Keywords: thyroid modality; endocrine disrupting; statistical power; disrupting properties ... See more keywords