Ancillary molecular testing of indeterminate thyroid nodules
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DOI: 10.1002/cncy.22012
Abstract: Cytological specimens from thyroid nodules are increasingly being adopted as the first available material for cost effectively managing patients in the era of personalized medicine. Cytology aspirates not only play a central role in providing… read more here.
Keywords: thyroid nodules; indeterminate thyroid; molecular testing; ancillary molecular ... See more keywords
Can ultrasound systems for risk stratification of thyroid nodules identify follicular carcinoma?
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DOI: 10.1002/cncy.22235
Abstract: Ultrasound (US) risk stratification systems (RSSs) have been developed to reduce the number of unnecessary fine needle aspirations (FNAs) of thyroid nodules. These systems were designed primarily to identify papillary thyroid carcinomas, thus their performance… read more here.
Keywords: thyroid nodules; risk stratification; carcinoma; thyroid ... See more keywords
Subtype of atypia on cytology and risk of malignancy in pediatric thyroid nodules
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DOI: 10.1002/cncy.22544
Abstract: Thyroid nodules with atypia of undetermined significance (AUS) are challenging to manage because of their intermediate risk of malignancy. Subclassification of atypia can refine malignancy risk in adult AUS nodules but has not been evaluated… read more here.
Keywords: thyroid nodules; subtype atypia; risk malignancy; risk ... See more keywords
Preoperative diagnosis of thyroid nodules: An integrated multidisciplinary approach
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DOI: 10.1002/cncy.22546
Abstract: Because of the coronavirus disease 2019 pandemic, the joint session between the European Society of Pathology Working Groups of Endocrine Pathology and Cytopathology, initially scheduled in Glasgow (United Kingdom) for September 1, 2020, was converted… read more here.
Keywords: thyroid nodules; nodules integrated; integrated multidisciplinary; pathology ... See more keywords
Risk stratification of cytologically indeterminate thyroid nodules with nondiagnostic or benign cytology on repeat FNA: Implications for molecular testing and surveillance
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Cytopathology"
DOI: 10.1002/cncy.22684
Abstract: Evidence guiding the management of cytologically indeterminate thyroid nodules with nondiagnostic (ND) or benign cytology on repeat fine‐needle aspiration (FNA) is limited. This study evaluates the utility of molecular testing and estimates the risk of… read more here.
Keywords: thyroid nodules; cytologically indeterminate; thyroid; nodules nondiagnostic ... See more keywords
American College of Radiology–Developed Thyroid Imaging Reporting and Data System 3, 4, and 5 thyroid nodules are distinctive by cytology, genetic imprints, and histology
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DOI: 10.1002/cncy.70050
Abstract: Thyroid nodules, found in up to 68% of adults, can be risk‐stratified by high‐resolution ultrasound. This study evaluates the concordance between “suspicious” Thyroid Imaging Reporting and Data System (TI‐RADS) 3–5 nodules and cytologic and molecular… read more here.
Keywords: thyroid nodules; histology; imaging reporting; cytology ... See more keywords
On the Identification of Thyroid Nodules using Semi-Supervised Deep Learning.
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DOI: 10.1002/cnm.3433
Abstract: Detecting malign cases from thyroid nodule examinations is crucial in healthcare particularly to improve the early detection of such cases. However, malign thyroid nodules can be extremely rare and is hard to find using the… read more here.
Keywords: thyroid nodules; nodules using; identification thyroid; thyroid ... See more keywords
Hybrid deep learning assisted multi classification: Grading of malignant thyroid nodules
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DOI: 10.1002/cnm.3824
Abstract: Thyroid nodules are commonly diagnosed with ultrasonography, which includes internal characteristics, varying looks, and hazy boundaries, making it challenging for a clinician to differentiate between malignant and benign forms based only on visual identification. The… read more here.
Keywords: classification; deep learning; malignant thyroid; thyroid nodules ... See more keywords
Risk factors associated with malignancy and with triage to surgery in thyroid nodules classified as Bethesda category IV (FN/SFN)
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DOI: 10.1002/dc.23923
Abstract: Thyroid nodules diagnosed as Bethesda category IV [follicular neoplasm/suspicious for follicular neoplasm (FN/SFN)] are recommended for surgery. However, only 10%‐40% of these nodules turn out to be malignant on histopathological examination. Therefore, selection for surgery… read more here.
Keywords: thyroid nodules; triage surgery; surgery; bethesda category ... See more keywords
Determining the molecular test for indeterminate thyroid nodules best suited for our practice: A quality assurance study
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DOI: 10.1002/dc.24091
Abstract: Currently, molecular studies are widely used as a guiding tool in further management of cytologically indeterminate thyroid nodules. At our institution, clinicians have recently expressed concern over receiving “less positive molecular results” upon switching from… read more here.
Keywords: thyroid nodules; determining molecular; test indeterminate; indeterminate thyroid ... See more keywords
Performance of Afirma genomic sequencing classifier vs gene expression classifier in Bethesda category III thyroid nodules: An institutional experience
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DOI: 10.1002/dc.24765
Abstract: Afirma gene expression classifier (GEC) is an adjunct to thyroid fine needle aspiration shown to improve pre‐operative risk assessment and reduce unnecessary surgery of indeterminate thyroid nodules. Genomic sequencing classifier (GSC) is a newer version… read more here.
Keywords: thyroid nodules; genomic sequencing; gene expression; sequencing classifier ... See more keywords