In vitro assessment of thyroid peroxidase inhibition by chemical exposure: comparison of cell models and detection methods
Sign Up to like & getrecommendations! Published in 2024 at "Archives of Toxicology"
DOI: 10.1007/s00204-024-03766-7
Abstract: Disruption of the thyroid hormone (TH) system is connected with diverse adverse health outcomes in wildlife and humans. It is crucial to develop and validate suitable in vitro assays capable of measuring the disruption of… read more here.
Keywords: thyroid peroxidase; inhibition; cell; thyroid ... See more keywords
In silico prediction models for thyroid peroxidase inhibitors and their application to synthetic flavors
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DOI: 10.1007/s10068-022-01041-y
Abstract: Systematic toxicity tests are often waived for the synthetic flavors as they are added in a very small amount in foods. However, their safety for some endpoints such as endocrine disruption should be concerned as… read more here.
Keywords: synthetic flavors; models thyroid; prediction models; silico prediction ... See more keywords
Establishing thresholds and effects of gender, age, and season for thyroglobulin and thyroid peroxidase antibodies by mining real-world big data.
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DOI: 10.1016/j.clinbiochem.2019.08.011
Abstract: BACKGROUND Thyroglobulin antibody (TG-Ab) and thyroid peroxidase antibody (TPO-Ab) are cornerstone biomarkers for autoimmune thyroid diseases, and establishment of appropriate thresholds is crucial for physicians to appropriately interpret test results. Therefore, we established the thresholds… read more here.
Keywords: biochemistry; big data; age; gender age ... See more keywords
Oatmeal and wheat flour as the sources of thyroid peroxidase and proinflammatory enzymes modulators in the prevention of thyroid diseases
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DOI: 10.1038/s41598-025-85848-9
Abstract: Polyphenolic plant compounds possess nutritional and pro-healthy potential, reducing the risk of auto-inflammatory and neoplastic diseases. However, their interference with the progression of thyroid gland dysfunctions has remained largely unaddressed. For this purpose, we combined… read more here.
Keywords: thyroid peroxidase; thyroid diseases; oatmeal wheat; thyroid ... See more keywords
Thyroid peroxidase identified in human granulosa cells: another piece to the thyroid-ovary puzzle?
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DOI: 10.1080/09513590.2017.1296424
Abstract: Abstract Thyroid hormones seemingly influence the maturation of the human oocyte. Thyroid hormone receptors have been isolated in granulosa mural and cumulus cells and the mature oocyte of the human ovarian follicle. Thyroid hormones are… read more here.
Keywords: granulosa cells; granulosa; thyroid hormones; thyroid peroxidase ... See more keywords
A-046 Evaluation of the Clinical Performance of Anti Thyroid Peroxidase II and Anti Thyroglobulin II Assays on the ADVIA Centaur System
Sign Up to like & getrecommendations! Published in 2025 at "Clinical Chemistry"
DOI: 10.1093/clinchem/hvaf086.045
Abstract: Autoimmune thyroid diseases (AITD), including Hashimoto’s thyroiditis (HT) and Graves* disease (GD), are characterized by the presence of autoantibodies against thyroid-specific proteins, such as thyroid peroxidase (TPO) and thyroglobulin (Tg). These autoantibodies play a critical… read more here.
Keywords: centaur; thyroid peroxidase; anti; assays advia ... See more keywords
Identification of metastatic papillary thyroid carcinoma in FNA specimens using thyroid peroxidase immunohistochemistry
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DOI: 10.1111/cyt.12531
Abstract: We evaluated immunohistochemical staining for thyroid peroxidase (TPO), a glycoprotein found in the apical plasma membrane of thyroid follicular cells, as a marker for metastatic PTC in FNA samples and compared results with thyroglobulin (Tg)… read more here.
Keywords: fna; peroxidase; metastatic papillary; thyroid peroxidase ... See more keywords
Inflammatory Immune Markers Associated With Thyroid Peroxidase Autoantibodies in Children Diagnosed With Both Type 1 Diabetes and Celiac Disease
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DOI: 10.1111/sji.70015
Abstract: Autoimmune thyroid disease (AITD) is associated with other autoimmune endocrine diseases such as type 1 diabetes (T1D) and celiac disease (CeD). Thyroid peroxidase autoantibodies (TPOA) are biomarkers of AITD but may also occur in patients… read more here.
Keywords: disease; thyroid peroxidase; peroxidase autoantibodies; immune markers ... See more keywords
Relationship between Gene Polymorphisms and Urine Iodine Levels on Susceptibility to Thyroid Peroxidase Antibody Positivity in the Chinese Population
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DOI: 10.1159/000506701
Abstract: Background/Aims: Hashimoto thyroiditis, characterized by positive thyroid peroxidase antibodies (TPOAbs), is caused by the interaction of genetic and environment factors. The aim of this study was to clarify the interaction of gene polymorphisms and iodine… read more here.
Keywords: risk; thyroid peroxidase; positivity; tpoab ... See more keywords
Development and validation of an ELISA for a biomarker of thyroid dysfunction, thyroid peroxidase autoantibodies (TPO-Ab), in dried blood spots
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Physiological Anthropology"
DOI: 10.1186/s40101-020-00228-8
Abstract: Background The prevalence of allergic and autoimmune conditions has been steadily increasing in wealthy nations over the past century. One hypothesis put forward to explain this is the Old Friends Hypothesis, which posits that increased… read more here.
Keywords: validation; dbs samples; dried blood; dbs ... See more keywords
Thyroid peroxidase (TPO) expressed in thyroid and breast tissues shows similar antigenic properties
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DOI: 10.1371/journal.pone.0179066
Abstract: Background Thyroid peroxidase (TPO) is essential for physiological function of the thyroid gland. The high prevalence of thyroid peroxidase antibodies (TPOAbs) in patients with breast cancer and their protective role had previously been demonstrated, indicating… read more here.
Keywords: thyroid peroxidase; breast; breast cancer; tpo ... See more keywords