Di(2‐ethylhexyl) phthalate induced thyroid toxicity via endoplasmic reticulum stress: In vivo and in vitro study
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23648
Abstract: Di(2‐ethylhexyl) phthalate (DEHP) could induce thyroid injury but the mechanism was unclear. This study combined in vivo and in vitro experiments to clarify the mechanism. In vivo, the offspring of Sprague Dawley rats were gavaged… read more here.
Keywords: vitro; stress; ethylhexyl phthalate; toxicity ... See more keywords
Benchmark dose analysis of multiple thyroid toxicity endpoints in ovariectomized rats exposed to propylthiouracil
Sign Up to like & getrecommendations! Published in 2018 at "Regulatory Toxicology and Pharmacology"
DOI: 10.1016/j.yrtph.2018.06.013
Abstract: ABSTRACT Benchmark dose (BMD) analysis is generally recognized superior to generate a point of departure (PoD) to conduct risk assessment on environmental toxicants, comparing with the traditionally employed no observed adverse effect level (NOAEL) or… read more here.
Keywords: thyroid toxicity; analysis; benchmark dose; toxicity endpoints ... See more keywords