TIA1 variant drives myodegeneration in multisystem proteinopathy with SQSTM1 mutations
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DOI: 10.1172/jci97103
Abstract: Multisystem proteinopathy (MSP) involves disturbances of stress granule (SG) dynamics and autophagic protein degradation that underlie the pathogenesis of a spectrum of degenerative diseases that affect muscle, brain, and bone. Specifically, identical mutations in the… read more here.
Keywords: tia1 variant; tia1 n357s; multisystem proteinopathy; sqstm1 ... See more keywords