A Comparative Study on Ticagrelor and Clopidogrel in Patients With Acute Coronary Syndrome Treated With Primary Percutaneous Coronary Intervention.
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DOI: 10.1002/jcph.2239
Abstract: To compare the efficacy and safety of ticagrelor and clopidogrel in patients with acute coronary syndrome (ACS) treated with primary percutaneous coronary intervention (PPCI). 3,528 consecutive patients with ACS treated with PPCI were divided into… read more here.
Keywords: ticagrelor; ticagrelor clopidogrel; clopidogrel patients; clopidogrel ... See more keywords
Pharmacodynamic Effects of Switching From Ticagrelor to Clopidogrel in Patients With Coronary Artery Disease: Results of the SWAP-4 Study
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DOI: 10.1161/circulationaha.118.033983
Abstract: Background: Switching between different classes of P2Y12 inhibitors, including de-escalation from ticagrelor to clopidogrel, commonly occurs in clinical practice. However, the pharmacodynamic profiles of this strategy have been poorly explored. Methods: This was a prospective,… read more here.
Keywords: ticagrelor clopidogrel; platelet; group; 24h group ... See more keywords
Comparison of ticagrelor and clopidogrel in the treatment of patients with coronary heart disease carrying CYP2C19 loss of function allele
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DOI: 10.21037/jtd-22-740
Abstract: Background Clopidogrel is a traditional P2Y12 receptor inhibitor that is widely used in clinical practice, but there are significant individual differences in its therapeutic effect. Carriers of the CYP2C19 deletion allele have a higher risk… read more here.
Keywords: ticagrelor; prognosis; ticagrelor clopidogrel; disease ... See more keywords
Comparing the effectiveness and safety of dual antiplatelet with ticagrelor or clopidogrel in elderly Asian patients with acute myocardial infraction
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DOI: 10.3389/fcvm.2023.1143509
Abstract: Background Current guidelines recommend potent P2Y12 inhibitors for patients after acute coronary syndrome. However, the data on the efficacy and safety of potent P2Y12 inhibitors in elderly Asian populations was limited. We aimed to investigate… read more here.
Keywords: elderly asian; ticagrelor; ticagrelor clopidogrel; clopidogrel ... See more keywords
Adverse reaction signals mining and hemorrhagic signals comparison of ticagrelor and clopidogrel: A pharmacovigilance study based on FAERS
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.970066
Abstract: Background: Ticagrelor and clopidogrel are commonly used antiplatelet agents, and we conducted a pharmacovigilance analysis using the Food and Drug Administration Adverse Event Reporting System (FAERS) to provide a reference for safe and reasonable clinical… read more here.
Keywords: ticagrelor; ror prr; ticagrelor clopidogrel; hemorrhagic signals ... See more keywords
Comparison of atrial fibrillation predictors in patients with acute coronary syndrome using ticagrelor or clopidogrel
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DOI: 10.3906/sag-1903-188
Abstract: Background/aim Ticagrelor is a drug widely used in patients with acute coronary syndromes (ACS) that specifically increases the plasma level of adenosine, which is likely to cause atrial fibrillation (AF). Therefore, in this study we… read more here.
Keywords: atrial fibrillation; clopidogrel; patients acute; ticagrelor clopidogrel ... See more keywords
DAPT de-escalation from ticagrelor to clopidogrel 1 mo after PCI for acute MI reduced net clinical events at 1 y
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Internal Medicine"
DOI: 10.7326/j22-0002
Abstract: SOURCE CITATION Kim CJ, Park MW, Kim MC, et al. Unguided de-escalation from ticagrelor to clopidogrel in stabilised patients with acute myocardial infarction undergoing percutaneous coronary intervention (TALOS-AMI): an investigator-initiated, open-label, multicentre, non-inferiority, randomised trial.… read more here.
Keywords: ticagrelor clopidogrel; escalation ticagrelor; dapt escalation;