Articles with "tie1 function" as a keyword



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Preclinical validation of a novel metastasis‐inhibiting Tie1 function‐blocking antibody

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Published in 2020 at "EMBO Molecular Medicine"

DOI: 10.15252/emmm.201911164

Abstract: The angiopoietin (Ang)–Tie pathway has been intensely pursued as candidate second‐generation anti‐angiogenic target. While much of the translational work has focused on the ligand Ang2, the clinical efficacy of Ang2‐targeting drugs is limited and failed… read more here.

Keywords: function blocking; metastasis; tie1; tie1 function ... See more keywords