TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation
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DOI: 10.1002/1873-3468.70110
Abstract: A signal transduction pathway has been defined in which ADP‐heptose activates the mammalian protein kinase ALPK1, which phosphorylates the adaptor protein TIFA, inducing its polymerisation and interaction with the E3 ubiquitin ligases TRAF2/c‐IAP1 and TRAF6.… read more here.
Keywords: degradation; tifa via; binds tifa; via novel ... See more keywords