Dynamic ROS Regulation by TIGAR: Balancing Anti-cancer and Pro-metastasis Effects.
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DOI: 10.1016/j.ccell.2020.01.009
Abstract: The role of ROS in cancer is complex, with studies demonstrating both pro- and anti-tumor effects. In a pancreatic ductal adenocarcinoma model, ROS limitation through TIGAR has been shown to initially support cancer development but… read more here.
Keywords: tigar; ros regulation; tigar balancing; cancer ... See more keywords