Tightening a deadly pore former
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DOI: 10.1038/s41589-019-0235-4
Abstract: A small molecule was identified that binds to a unique site on the pro-apoptotic protein BAX, stabilizing the protein structure allosterically and preventing the conformational activation to a pore former by BH3 proteins. read more here.
Keywords: tightening deadly; deadly pore; pore former; biology ... See more keywords