The L1-ORF1p coiled coil enables formation of a tightly compacted nucleic acid-bound complex that is associated with retrotransposition
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DOI: 10.1093/nar/gkac628
Abstract: Abstract Long interspersed nuclear element 1 (L1) parasitized most vertebrates and constitutes ∼20% of the human genome. It encodes ORF1p and ORF2p which form an L1-ribonucleoprotein (RNP) with their encoding transcript that is copied into… read more here.
Keywords: retrotransposition; coiled coil; tightly compacted; nucleic acid ... See more keywords