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Published in 2022 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-22-0473
Abstract: Ellegast and colleagues show that monocytic acute myeloid leukemias (AML), enriched in inflammatory and immune gene sets, exploit a transcriptional repressor-namely, IRF2BP2-to mitigate their cell-intrinsic inflammatory output and ensure their maintenance. IRF2BP2 ablation results in…
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Keywords:
tightrope balancing;
acute;
walking tightrope;
acute myeloid ... See more keywords