TIGIT Blockade and IL15 in Tumor Immunotherapy: Together is Better
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DOI: 10.1158/1078-0432.ccr-20-2538
Abstract: IL15 and TIGIT blockade enhances the natural killer (NK) cell–mediated activity against MHC-I–deficient melanoma both in vitro and in preclinical models. IL15-induced harnessing of NK cells, associated with their unleashing by TIGIT blockade, may represent… read more here.
Keywords: tumor immunotherapy; blockade il15; tigit; tigit blockade ... See more keywords
Low-dose immunogenic chemotherapeutics promotes immune checkpoint blockade in microsatellite stability colon cancer
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DOI: 10.3389/fimmu.2022.1040256
Abstract: More than 85% of colorectal cancer (CRC) patients, who are with microsatellite stability (MSS), are resistant to immune checkpoint blockade (ICB) treatment. To overcome this resistance, combination therapy with chemotherapy is the most common choice.… read more here.
Keywords: immune checkpoint; tigit blockade; blockade; checkpoint blockade ... See more keywords
TIGIT Blockade Exerts Synergistic Effects on Microwave Ablation Against Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.832230
Abstract: Background Combination immunotherapy based on immune checkpoint inhibitors (ICIs) has shown great success in the treatment of many types of cancers and has become the mainstream in the comprehensive treatment of cancers. Ablation in combination… read more here.
Keywords: tigit blockade; mwa; tumor; combination ... See more keywords