Higher TIGIT+CD226- γδ T cells in Patients with Acute Myeloid Leukemia.
Sign Up to like & getrecommendations! Published in 2020 at "Immunological investigations"
DOI: 10.1080/08820139.2020.1806868
Abstract: The diverse structural and functional heterogeneity of γδ T cells is related to their distinct role in cancer immunity. The different phenotypes of γδ T cells in patients with acute myeloid leukemia (AML) is far… read more here.
Keywords: cd226 cells; myeloid leukemia; tigit cd226; acute myeloid ... See more keywords
TIGIT-Fc Prolongs Corneal Allograft Survival in Mice by Upregulating TIGIT/CD226 Expression and the Proportion of Helios+Foxp3+ Treg Cells
Sign Up to like & getrecommendations! Published in 2022 at "Transplantation"
DOI: 10.1097/tp.0000000000004257
Abstract: Background. Reduction of graft rejection remains key issue for supporting long-term graft retention after corneal transplantation. The relevance of Treg in reduction of corneal allografts rejection has been demonstrated. It has been recently reported that… read more here.
Keywords: treg cells; tigit treatment; corneal; foxp3 treg ... See more keywords
Expression of the immune checkpoint molecules CD226 and TIGIT in preeclampsia patients
Sign Up to like & getrecommendations! Published in 2024 at "BMC Immunology"
DOI: 10.1186/s12865-024-00603-5
Abstract: Background Imbalanced immune responses are involved in developing preeclampsia (PE). We wish to explore the expression and potential changes of immune checkpoint molecules TIGIT, CD226 and CD155 in PE patients. Methods The expression of the… read more here.
Keywords: immune checkpoint; tigit cd226; cd226 cd155; checkpoint molecules ... See more keywords
The immunomodulatory molecule TIGIT is expressed by chronic lymphocytic leukemia cells and contributes to anergy.
Sign Up to like & getrecommendations! Published in 2023 at "Haematologica"
DOI: 10.3324/haematol.2022.282177
Abstract: T-cell immunoreceptor with Ig and ITIM domains (TIGIT) is an inhibitory checkpoint receptor that negatively regulates T cell responses. CD226 competes with TIGIT for binding to the CD155 ligand, delivering a positive signal to the… read more here.
Keywords: cell; lymphocytic leukemia; tigit; expression ... See more keywords
Examination of the TIGIT-CD226-CD112-CD155 Immune Checkpoint Network during a Healthy Pregnancy
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231810776
Abstract: Background: The importance of immune checkpoint molecules is well known in tumor and transplantation immunology; however, much less information is available regarding human pregnancy. Despite the significant amount of information about the TIGIT and CD226… read more here.
Keywords: immune checkpoint; checkpoint; pregnancy; tigit cd226 ... See more keywords
TIGIT/CD226 Axis Regulates Anti-Tumor Immunity
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceuticals"
DOI: 10.3390/ph14030200
Abstract: Tumors escape immune surveillance by inducing various immunosuppressive pathways, including the activation of inhibitory receptors on tumor-infiltrating T cells. While monoclonal antibodies (mAbs) blocking programmed cell death 1 (PD-1), programmed death-ligand 1 (PD-L1), and cytotoxic… read more here.
Keywords: immunity; cd226 axis; axis regulates; cancer ... See more keywords