TIGIT as a Promising Therapeutic Target in Autoimmune Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.911919
Abstract: Co-inhibitory receptors (IRs) are molecules that protect host against autoimmune reactions and maintain peripheral self-tolerance, playing an essential role in maintaining immune homeostasis. In view of the substantial clinical progresses of negative immune checkpoint blockade… read more here.
Keywords: therapeutic target; autoimmune diseases; target autoimmune; autoimmune ... See more keywords
TIGIT: A promising target to overcome the barrier of immunotherapy in hematological malignancies
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1091782
Abstract: Immune evasion through up-regulating checkpoint inhibitory receptors on T cells plays an essential role in tumor initiation and progression. Therefore, immunotherapy, including immune checkpoint inhibitor targeting programmed cell death protein 1 (PD-1) and chimeric antigen… read more here.
Keywords: overcome barrier; promising target; target overcome; hematological malignancies ... See more keywords