Anti-HIV Tigliane Diterpenoids from Wikstroemia scytophylla.
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DOI: 10.1021/acs.jnatprod.0c00700
Abstract: During a chemical investigation of Wikstroemia scytophylla, three new [wikstrocins A-C (1-3)] and three known tigliane diterpenoids (4-6) were isolated. The structures of the new compounds were elucidated from extensive physiochemical and spectroscopic analysis. The… read more here.
Keywords: wikstroemia scytophylla; tigliane diterpenoids; hiv; anti hiv ... See more keywords
LC-MS Identification, Isolation, and Structural Elucidation of Anti-HIV Tigliane Diterpenoids from Wikstroemia lamatsoensis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.1c00570
Abstract: Structurally diverse tigliane diterpenoids have drawn significant research interest for drug discovery over many decades. Using LC-MS-guided fractionation and separation, the first phytochemical investigation on Wikstroemia lamatsoensis led to the isolation of eight tiglianes (1-8),… read more here.
Keywords: tigliane diterpenoids; isolation; wikstroemia lamatsoensis; anti hiv ... See more keywords
Tigliane Diterpenoids with Larvicidal, Antifungal, and α-Glucosidase Inhibitory Activities from Croton damayeshu.
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DOI: 10.1021/acs.jnatprod.1c00977
Abstract: Thirty-five tigliane diterpenoids and two ent-kaurane diterpenoids were isolated from the leaves of Croton damayeshu, and, among them, compounds 1-10 were characterized as new tigliane diterpenoids. The structures of compounds 1-10 were determined by analysis… read more here.
Keywords: glucosidase inhibitory; antifungal glucosidase; tigliane diterpenoids; larvicidal antifungal ... See more keywords
Cytotoxic Tigliane Diterpenoids from Croton damayeshu.
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DOI: 10.1021/acs.jnatprod.9b00042
Abstract: Chemical investigation of an EtOH extract of the twigs and leaves of Croton damayeshu afforded 10 new tigliane diterpenoids, crodamoids A-J (1-10), along with five known compounds. Their structures were elucidated by physical data analysis.… read more here.
Keywords: tigliane diterpenoids; diterpenoids croton; croton damayeshu; cytotoxic tigliane ... See more keywords
Natural and Semisynthetic Tigliane Diterpenoids with New Carbon Skeletons from Euphorbia dracunculoides as a Wnt Signaling Pathway Inhibitor.
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DOI: 10.1021/acs.orglett.7b01813
Abstract: Euphordraculoates A (1) and B (2), featuring tigliane diterpenoids with two new carbon skeletons, were characterized as metabolites of Euphorbia dracunculoides and semisynthetic products, respectively. Their structures were determined by spectroscopic analyses and X-ray crystallography.… read more here.
Keywords: tigliane diterpenoids; new carbon; carbon skeletons; euphorbia dracunculoides ... See more keywords