Relationship of the standard uptake value of 18F-FDG-PET-CT with tumor-infiltrating lymphocytes in breast tumors measuring ≥ 1 cm
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DOI: 10.1038/s41598-021-91404-y
Abstract: Evidence suggests that tumor cells and tumor-infiltrating lymphocytes (TILs) compete for glucose in the tumor microenvironment and that tumor metabolic parameters correlate with localized immune markers in several solid tumors. We investigated the relationship of… read more here.
Keywords: til levels; fdg pet; tumor infiltrating; 18f fdg ... See more keywords
Interaction between Molecular Subtypes and Stromal Immune Infiltration before and after Treatment in Breast Cancer Patients Treated with Neoadjuvant Chemotherapy
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DOI: 10.1158/1078-0432.ccr-18-3017
Abstract: Purpose: High levels of tumor-infiltrating lymphocytes (TIL) before neoadjuvant chemotherapy (NAC) are associated with higher pathologic complete response (pCR) rates and better survival in triple-negative breast cancer (TNBC) and HER2-positive breast cancer. We investigated the… read more here.
Keywords: til levels; breast; breast cancer; nac ... See more keywords
Differences in immune-related gene expressions and tumor-infiltrating lymphocytes according to chemotherapeutic response in ovarian high-grade serous carcinoma
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DOI: 10.1186/s13048-020-00667-y
Abstract: Background High-grade serous carcinoma (HGSC) of the ovary is the most common subtype of epithelial ovarian cancer (EOC) and has an overall poor prognosis. There is increasing awareness of the importance of immune cell populations… read more here.
Keywords: related gene; gene expressions; response; immune related ... See more keywords
No Impact of Smoking Status on Breast Cancer Tumor Infiltrating Lymphocytes, Response to Neoadjuvant Chemotherapy and Prognosis
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DOI: 10.3390/cancers12102943
Abstract: Simple Summary Tobacco use is associated with an increase in breast cancer mortality. Pathologic complete response (pCR) rate to neoadjuvant chemotherapy is influenced by tumor-infiltrating lymphocyte (TIL) levels and is associated with a better long-term… read more here.
Keywords: status; response; til levels; smoking status ... See more keywords
Negative Relationship between Post-Treatment Stromal Tumor-Infiltrating Lymphocyte (TIL) and Survival in Triple-Negative Breast Cancer Patients Treated with Dose-Dense Dose-Intense NeoAdjuvant Chemotherapy
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DOI: 10.3390/cancers14051331
Abstract: Simple Summary Triple-negative breast cancer (TNBC) continues to have a poor prognosis unless a complete pathological response is achieved after neoadjuvant chemotherapy (NAC). The identification of prognostic factors would help to improve care. The evaluation… read more here.
Keywords: til; dose; nac; til levels ... See more keywords
Prognostic Relevance of Nuclear Receptors in Relation to Peritumoral Inflammation and Tumor Infiltration by Lymphocytes in Breast Cancer
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DOI: 10.3390/cancers14194561
Abstract: Simple Summary The aim of this study was to investigate the prognostic impact of tumor-infiltrating lymphocytes (TILs) in a panel of 264 sporadic breast cancers by quantifying TIL levels according to Salgado and correlate this… read more here.
Keywords: nuclear receptors; peritumoral inflammation; til levels; breast cancer ... See more keywords
Deep Learning with Transformer or Convolutional Neural Network in the Assessment of Tumor-Infiltrating Lymphocytes (TILs) in Breast Cancer Based on US Images: A Dual-Center Retrospective Study
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DOI: 10.3390/cancers15030838
Abstract: Simple Summary Tumor-infiltrating lymphocytes (TILs) have been proven to be promising biomarkers associated with therapeutic outcomes and prognosis in breast cancer patients. Increased TIL levels predicted a higher rate of response to neoadjuvant chemotherapy in… read more here.
Keywords: cancer; til levels; breast cancer; deep learning ... See more keywords