Adoptive cell transfer therapy for melanoma
Sign Up to like & getrecommendations! Published in 2022 at "Experimental Dermatology"
DOI: 10.1111/exd.14707
Abstract: Adoptive cell transfer (ACT) of tumor‐infiltrating lymphocytes (TILs) for melanoma is an example of the most successful cancer immune therapy. It achieves a durable complete response about ~20% of patients, and they might be cured.… read more here.
Keywords: adoptive cell; cell transfer; therapy; til therapy ... See more keywords
Adoptive transfer of tumor-infiltrating lymphocytes in melanoma: a viable treatment option
Sign Up to like & getrecommendations! Published in 2018 at "Journal for Immunotherapy of Cancer"
DOI: 10.1186/s40425-018-0391-1
Abstract: The treatment of metastatic melanoma patients with autologous tumor-infiltrating lymphocytes (TIL) shows robust, reproducible, clinical responses in clinical trials executed in several specialized centers over the world. Even in the era of targeted therapy and… read more here.
Keywords: infiltrating lymphocytes; til therapy; treatment; tumor infiltrating ... See more keywords
A phase II study of autologous tumor infiltrating lymphocytes (TIL, LN-144/LN-145) in patients with solid tumors.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.tps2648
Abstract: TPS2648 Background: Adoptive cell therapy (ACT) with tumor infiltrating lymphocytes (TIL) has demonstrated durable complete responses in immunogenic tumors with high mutational burden in metastatic melanoma patients who had not received prior immune checkpoint inhibitors… read more here.
Keywords: infiltrating lymphocytes; 144 145; therapy; til therapy ... See more keywords
TIL therapy and anti-CTLA4: can they co-exist?
Sign Up to like & getrecommendations! Published in 2019 at "Oncotarget"
DOI: 10.18632/oncotarget.26509
Abstract: Adoptive transfer of tumor-infiltrating lymphocytes (TIL ACT) is one of the first living immunotherapies to be tested in multiple clinical trials in metastatic melanoma and results consistently in a 40 to 50% overall response rate… read more here.
Keywords: til therapy; anti ctla4; checkpoint;
INTEGRATING BIOREACTOR SYSTEM TO SPEED UP TUMOUR INFILTRATING LYMPHOCYTES (TILS) IMMUNOTHERAPY COMMERCIALIZATION
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Applied Pharmaceutics"
DOI: 10.22159/ijap.2020v12i4.37244
Abstract: One of the major breakthroughs on adoptive cell transfer (ACT) is autologous T cells transfer that either derived from tumour infiltrating lymphocytes (TILs) or genetically engineered T cells, which express tumour recognizing receptors. Between those… read more here.
Keywords: tumour infiltrating; lymphocytes tils; infiltrating lymphocytes; til therapy ... See more keywords