Tilorone confers robust in vitro and in vivo antiviral effects against severe fever with thrombocytopenia syndrome virus
Sign Up to like & getrecommendations! Published in 2022 at "Virologica Sinica"
DOI: 10.1016/j.virs.2022.01.014
Abstract: Highlights • Tilorone dihydrochloride possesses robust anti-SFTSV activity in vitro and in vivo.• Intraperitoneal administration of tilorone leads to protection against intracranial lethal challenge of SFTSV.• The anti-SFTSV mechanism of tilorone is through stimulation of… read more here.
Keywords: vitro vivo; confers robust; tilorone confers; tilorone ... See more keywords
Old Drug, New Trick: Tilorone, a Broad-Spectrum Antiviral Drug as a Potential Anti-Fibrotic Therapeutic for the Diseased Heart
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceuticals"
DOI: 10.3390/ph14030263
Abstract: Cardiac fibrosis is associated with most forms of cardiovascular disease. No reliable therapies targeting cardiac fibrosis are available, thus identifying novel drugs that can resolve or prevent fibrosis is needed. Tilorone, an antiviral agent, can… read more here.
Keywords: anti fibrotic; fibrosis; heart; drug ... See more keywords