Efficiently Targeting Metastatic Osteosarcoma, Neuroblastoma and Glioblastoma with Ex-Vivo Expanded Natural Killer Cells Combined with N-803 (ALT-803, IL-15 Superagonist) and TIM-3 Blockage
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DOI: 10.1016/j.bbmt.2018.12.543
Abstract: Background The overall survival rate for pediatric osteosarcoma (OS), neuroblastoma (NB) and glioblastoma (GBM) in children with relapsed/refractory and metastatic disease remains dismal. Our group has successfully expanded peripheral blood Natural Killer cells (exPBNK) with… read more here.
Keywords: osteosarcoma neuroblastoma; tim; natural killer; tim blockage ... See more keywords