Stendomycin selectively inhibits TIM23-dependent mitochondrial protein import.
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DOI: 10.1038/nchembio.2493
Abstract: Tim17 and Tim23 are the main subunits of the TIM23 complex, one of the two major essential mitochondrial inner-membrane protein translocon machineries (TIMs). No chemical probes that specifically inhibit TIM23-dependent protein import were known to… read more here.
Keywords: protein; protein import; tim23 dependent; tim23 complex ... See more keywords