Time–Kill Analysis of Ceftolozane/Tazobactam Efficacy Against Mucoid Pseudomonas aeruginosa Strains from Cystic Fibrosis Patients
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DOI: 10.1007/s40121-017-0176-8
Abstract: IntroductionMucoid Pseudomonas aeruginosa (MP) strains in cystic fibrosis (CF) patients are thought to initiate the chronic infection stage of CF and are associated with pulmonary function decline.ObjectivesThe purpose of this study was to assess the… read more here.
Keywords: tazobactam; kill analysis; ceftolozane tazobactam; time kill ... See more keywords
Effects of β-caryophyllene and Murraya paniculata essential oil in the murine hepatoma cells and in the bacteria and fungi 24-h time–kill curve studies
Sign Up to like & getrecommendations! Published in 2017 at "Pharmaceutical Biology"
DOI: 10.1080/13880209.2016.1254251
Abstract: Abstract Context: Orange Jessamine [Murraya paniculata L. (Rutaceae)] has been used worldwide in folk medicine as an anti-inflammatory, antibiotic and analgesic. Objective: The objective of this study is to investigate the in vitro antioxidant, cytotoxic,… read more here.
Keywords: essential oil; kill curve; time kill; activity ... See more keywords
Evaluation of dalbavancin alone and in combination with &bgr;-lactam antibiotics against resistant phenotypes of Staphylococcus aureus
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DOI: 10.1093/jac/dky376
Abstract: Background Emergence of reduced susceptibility to vancomycin warrants the development of new antimicrobial agents for the treatment of MRSA. We evaluated the activity of dalbavancin, a novel lipoglycopeptide antibiotic, both alone and combined with β-lactams,… read more here.
Keywords: combination; phenotypes staphylococcus; resistant phenotypes; dalbavancin ... See more keywords
In Vitro Time-Kill Studies of Trimethoprim/Sulfamethoxazole against Stenotrophomonas maltophilia versus Escherichia coli Using Cation-Adjusted Mueller-Hinton Broth and ISO-Sensitest Broth
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DOI: 10.1128/aac.02167-21
Abstract: Trimethoprim/sulfamethoxazole (TMP/SMZ) is considered the treatment of choice for infections caused by Stenotrophomonas maltophilia, but limited pharmacodynamic data are available to support current susceptibility breakpoints or guide optimal dosing. Time-kill studies using a TMP/SMZ concentration… read more here.
Keywords: time; tmp smz; stenotrophomonas maltophilia; time kill ... See more keywords
ATP Bioluminescence Assay To Evaluate Antibiotic Combinations against Extensively Drug-Resistant (XDR) Pseudomonas aeruginosa
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DOI: 10.1128/spectrum.00651-22
Abstract: Combining antibiotics is one of the few strategies available to overcome infections caused by multidrug-resistant bacteria. Time-kill curves are usually performed to evaluate antibiotic combinations, but obtaining results is too laborious to be routinely performed… read more here.
Keywords: kill curves; antibiotic combinations; method; time kill ... See more keywords
Time-Kill Kinetics of Lipid Fractions Isolated from Condiments against Foodborne Pathogens.
Sign Up to like & getrecommendations! Published in 2018 at "Food Technology and Biotechnology"
DOI: 10.17113/ftb.56.02.18
Abstract: Lipid fractions that are extracted from condiments have a wide array of biological potential and are commonly utilized for medicinal and culinary applications. This investigation aims at determining the antimicrobial potential of lipid fractions isolated… read more here.
Keywords: incubation; lipid fractions; fractions isolated; foodborne pathogens ... See more keywords
In vitro Evaluation of the Colistin-Carbapenem Combination in Clinical Isolates of A. baumannii Using the Checkerboard, Etest, and Time-Kill Curve Techniques
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2017.00209
Abstract: The worldwide increase in the emergence of carbapenem resistant Acinetobacter baumannii (CRAB) calls for the investigation into alternative approaches for treatment. This study aims to evaluate colistin-carbapenem combinations against Acinetobacter spp., in order to potentially… read more here.
Keywords: combination; colistin; colistin carbapenem; time kill ... See more keywords
Appraisal of selected ethnomedicinal plants as alternative therapies against onychomycosis: Evaluation of synergy and time-kill kinetics
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1067697
Abstract: Introduction: This study aims at the biological profiling of Allium sativum, Zingiber officinale, Nigella sativa, Curcuma longa, Mentha piperita, Withania somnifera, Azadirachta indica, and Lawsonia inermis as alternatives against onychomycosis to combat the treatment challenges.… read more here.
Keywords: time; kill kinetics; non dermatophytes; mge ... See more keywords
In silico genome-scale metabolic modeling and in vitro static time-kill studies of exogenous metabolites alone and with polymyxin B against Klebsiella pneumoniae
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.880352
Abstract: Multidrug-resistant (MDR) Klebsiella pneumoniae is a top-prioritized Gram-negative pathogen with a high incidence in hospital-acquired infections. Polymyxins have resurged as a last-line therapy to combat Gram-negative “superbugs”, including MDR K. pneumoniae. However, the emergence of… read more here.
Keywords: pneumoniae; klebsiella pneumoniae; static time; time kill ... See more keywords
Pseudomonas aeruginosa PAO 1 In Vitro Time–Kill Kinetics Using Single Phages and Phage Formulations—Modulating Death, Adaptation, and Resistance
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DOI: 10.3390/antibiotics10070877
Abstract: Pseudomonas aeruginosa is responsible for nosocomial and chronic infections in healthcare settings. The major challenge in treating P. aeruginosa-related diseases is its remarkable capacity for antibiotic resistance development. Bacteriophage (phage) therapy is regarded as a… read more here.
Keywords: pseudomonas aeruginosa; phage; resistance; phage formulations ... See more keywords
In Vitro and In Silico Approaches for the Evaluation of Antimicrobial Activity, Time-Kill Kinetics, and Anti-Biofilm Potential of Thymoquinone (2-Methyl-5-propan-2-ylcyclohexa-2,5-diene-1,4-dione) against Selected Human Pathogens
Sign Up to like & getrecommendations! Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11010079
Abstract: Thymoquinone (2-methyl-5-propan-2-ylcyclohexa-2,5-diene-1,4-dione; TQ), a principal bioactive phytoconstituent of Nigella sativa essential oil, has been reported to have high antimicrobial potential. Thus, the current study evaluated TQ’s antimicrobial potential against a range of selected human pathogens… read more here.
Keywords: time; thymoquinone methyl; kill kinetics; anti biofilm ... See more keywords