Time to onset in statistical signal detection revisited: A follow‐up study in long‐term onset adverse drug reactions
Sign Up to like & getrecommendations! Published in 2019 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.4790
Abstract: In a previous study, we developed a signal detection method using the time to onset (TTO) of adverse drug reactions (ADRs). The aim of the current study was to investigate this method in a subset… read more here.
Keywords: drug reactions; study; drug; signal detection ... See more keywords
Reported time to onset of neurological adverse drug reactions among different age and gender groups using metoclopramide: an analysis of the global database Vigibase®.
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Clinical Pharmacology"
DOI: 10.1007/s00228-017-2407-z
Abstract: PurposeDespite FDA and EMA warnings of long-term use, little is known regarding the time to onset (TTO) of neurological adverse drug reactions (ADR) for metoclopramide. The aims of this study were, first, to evaluate whether… read more here.
Keywords: neurological adrs; age; time onset; age gender ... See more keywords
Time to onset and duration of botulinum toxin efficacy in movement disorders
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neurology"
DOI: 10.1007/s00415-022-10995-2
Abstract: Botulinum toxin (BoNT) is a valuable treatment in movement disorders; however, time to onset and duration of efficacy may widely differ among patients. We aimed to clarify the impact of main demographic and clinical features… read more here.
Keywords: time onset; toxin; onset duration; efficacy ... See more keywords
Effect of postinjection facial exercise on time of onset of botulinum toxin for glabella and forehead wrinkles: A randomized, controlled, crossover clinical trial
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2018.10.013
Abstract: Men, % 98.0 96.9 .65 Race, white, % 94.9 94.8 .97 Average age, y 70 67 .03 Average Breslow thickness, mm 3.9* 0.76 \.01 Lesion identified by patient, % 38.5 22.2 .01 VA primary care… read more here.
Keywords: exercise time; dermatology; effect postinjection; facial exercise ... See more keywords
Impact of Allograft Injury Time of Onset on the Development of Chronic Lung Allograft Dysfunction After Lung Transplantation
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Transplantation"
DOI: 10.1111/ajt.14066
Abstract: The impact of allograft injury time of onset on the risk of chronic lung allograft dysfunction (CLAD) remains unknown. We hypothesized that episodes of late‐onset (≥6 months) allograft injury would produce an augmented CXCR3/ligand immune… read more here.
Keywords: time onset; allograft injury; injury; lung ... See more keywords
Time‐to‐onset of treatment for hypertension and hyperlipidaemia in South African diabetes mellitus patients: A survival analysis using medicine claims data
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Pharmacy and Therapeutics"
DOI: 10.1111/jcpt.12844
Abstract: Hypertension and hyperlipidaemia have high prevalence among diabetics and increase patients’ risk of cardiovascular diseases, ultimately affecting prognosis negatively. Medicine claims data have gained prominence in the study of drug‐related events and outcomes. There is… read more here.
Keywords: medicine; claims data; hypertension hyperlipidaemia; time onset ... See more keywords
Time to onset of bisphosphonate-related osteonecrosis of the jaws: a multicentre retrospective cohort study.
Sign Up to like & getrecommendations! Published in 2017 at "Oral diseases"
DOI: 10.1111/odi.12632
Abstract: OBJECTIVES Osteonecrosis of the jaw (ONJ) is a potentially severe adverse effect of bisphosphonates (BP). Although the risk of ONJ increases with increasing duration of BP treatment, there are currently no reliable estimates of the… read more here.
Keywords: onset bisphosphonate; risk; time; study ... See more keywords
Cost-effectiveness of recombinant tissue-type plasminogen activator for acute ischaemic stroke with unknown time of onset: a Markov modelling analysis from the Chinese and US perspectives
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Open"
DOI: 10.1136/bmjopen-2022-065133
Abstract: Objective The effectiveness of MRI-guided intravenous recombinant tissue-type plasminogen activator (r-tPA) for acute ischaemic stroke (AIS) with an unknown time of onset has been demonstrated by the WAKE-UP Trial. We aim to evaluate its long-term… read more here.
Keywords: unknown time; cost; time onset; intravenous tpa ... See more keywords
Estimating the time of onset of testicular torsion using ultrasonography in an experimental rat model
Sign Up to like & getrecommendations! Published in 2020 at "Ultrasonography"
DOI: 10.14366/usg.19055
Abstract: Purpose We aimed to document the time of onset of ultrasonographic and histologic changes in the testes of a rat model following testicular torsion. Methods Twenty-five Sprague-Dawley rats were divided into four groups. All animals… read more here.
Keywords: testicular torsion; torsion; time; time onset ... See more keywords
Time-to-onset of diabetes with everolimus use: analysis of a spontaneous reporting system database.
Sign Up to like & getrecommendations! Published in 2021 at "Die Pharmazie"
DOI: 10.1691/ph.2021.1624
Abstract: The incidence of hyperglycemia and diabetes induced by everolimus has been shown in previous studies. Our study analyzed diabetes time-to-onset profiles after everolimus use in patients who underwent transplantation and patients with cancer. Using data… read more here.
Keywords: everolimus use; time; transplantation; time onset ... See more keywords
Assessment of Time-to-onset and Outcome of Lung Adverse Events With Pomalidomide from a Pharmacovigilance Study
Sign Up to like & getrecommendations! Published in 2023 at "In Vivo"
DOI: 10.21873/invivo.13168
Abstract: Abstract Background/Aim: Pomalidomide is an immunomodulatory drug that is used to treat multiple myeloma. We examined the time-to-onset and outcome of lung adverse events (LAEs) related to pomalidomide in Japanese patients based on information obtained… read more here.
Keywords: time; onset outcome; pneumonia; outcome lung ... See more keywords