Impact of time in therapeutic range after left ventricular assist device placement: a comparison between thrombus and thrombus-free periods
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DOI: 10.1007/s11239-018-01800-x
Abstract: The association between time in therapeutic range (TTR) and clinical outcomes in patients with left ventricular assist devices (LVADs) on chronic warfarin therapy is not well understood. This study assessed TTR using the Rosendaal Method… read more here.
Keywords: time; period; thrombus free; time therapeutic ... See more keywords
Development and Implementation of National Time in Therapeutic Range Reports and Establishing Quality Standards Within Veterans Health Administration
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DOI: 10.1007/s11606-020-06422-9
Abstract: Warfarin had long been the sole oral anticoagulant until the advent of direct oral anticoagulants (DOACs). Improving the management of warfarin is an important goal because warfarin, or any anticoagulant, has the potential to cause… read more here.
Keywords: anticoagulation; quality; time therapeutic; therapeutic range ... See more keywords
Quality Improvement Program Improves Time in Therapeutic Range for Hemodialysis Recipients Taking Warfarin
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DOI: 10.1016/j.ekir.2019.10.011
Abstract: Introduction Studies have shown that achieving a time in therapeutic range (TTR) for warfarin of greater than 60% is associated with a lower risk of bleeding. However, many patients on hemodialysis (HD) do not achieve… read more here.
Keywords: improvement; quality improvement; time; time therapeutic ... See more keywords
Maximising Time in Therapeutic Range with Vitamin K Antagonists in LVAD Patients
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DOI: 10.1016/j.healun.2021.01.1950
Abstract: Purpose Time in Therapeutic range (TTR) is the percentage of time an anticoagulated patient has an INR between 2-3. While studies have demonstrated a link between low TTR, bleeding and thrombosis, the mean TTR in… read more here.
Keywords: time; time therapeutic; ttr; vad ... See more keywords
THE IMPACT OF TEMPORARY INTERRUPTIONS OF WARFARIN ON DOWNSTREAM TIME IN THERAPEUTIC RANGE IN PATIENTS WITH ATRIAL FIBRILLATION: RESULTS FROM ORBIT AF
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DOI: 10.1016/s0735-1097(19)31076-9
Abstract: Temporary interruption (TI) of warfarin in atrial fibrillation (AF) may be associated with subsequent sub- or supra-therapeutic INR. Our objective was to study time in therapeutic range (TTR) before and after a TI. AF patients… read more here.
Keywords: atrial fibrillation; therapeutic range; time therapeutic;
How good is time-in-therapeutic-range defined warfarin treatment compared to standard dose direct oral anticoagulants? Incidence of stroke in atrial fibrillation in a nationwide registry study
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DOI: 10.1093/europace/euad122.206
Abstract: Abstract Funding Acknowledgements Type of funding sources: Public hospital(s). Main funding source(s): The Finnish Foundation for Cardiovascular Research, and Helsinki and Uusimaa Hospital District research fund. Background and aims Direct oral anticoagulants (DOACs) have largely… read more here.
Keywords: standard dose; time therapeutic; ttr; direct oral ... See more keywords
Time in Therapeutic Range for Left Ventricular Assist Device Patients Anticoagulated With Warfarin: A Correlation to Clinical Outcomes
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DOI: 10.1097/mat.0000000000000449
Abstract: Left ventricular assist devices (LVADs) require anticoagulation therapy with vitamin K antagonists to reduce the risk of thrombotic events. The quality of anticoagulation may be assessed by the time in therapeutic range (TTR). We analyzed… read more here.
Keywords: time; time therapeutic; event; therapeutic range ... See more keywords
Time in Therapeutic Range for Bivalirudin Among Pediatric Ventricular Assist Device Recipients.
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DOI: 10.1097/mat.0000000000001261
Abstract: Given the adverse event rates involving bleeding and thrombosis among children on ventricular assist devices (VADs), anticoagulant management has become a focal point for quality improvement and innovation. There may be advantages to using direct… read more here.
Keywords: time therapeutic; ttr; ventricular assist; bivalirudin ... See more keywords
Is it Time for a Therapeutic Algorithm in Resected Pancreatic Ductal Adenocarcinoma?
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DOI: 10.1097/mpa.0000000000001449
Abstract: To the Editor: C onroy et al 1 report that modified FOLFIRINOX (the combination chemotherapy regimen with oxaliplatin, irinotecan, fluorouracil, and leucovorin) achieved a significant median disease-free survival (mDFS) of 21.6 months after a follow-up… read more here.
Keywords: time therapeutic; algorithm resected; ductal adenocarcinoma; pancreatic ductal ... See more keywords
Clinical Implications of Tacrolimus Time in Therapeutic Range and Intrapatient Variability in Urban Renal Transplant Recipients Undergoing Early Corticosteroid Withdrawal
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DOI: 10.1097/txd.0000000000001155
Abstract: Background. Tacrolimus demonstrates wide intrapatient and interpatient variability requiring therapeutic drug monitoring. The utility of tacrolimus time in therapeutic range (TTR) after renal transplantation (RT) under an early corticosteroid withdrawal (ECSWD) protocol is unknown. The… read more here.
Keywords: time therapeutic; tacrolimus time; ttr; variability ... See more keywords
Lower tacrolimus exposure and time in therapeutic range increase the risk of de novo donor‐specific antibodies in the first year of kidney transplantation
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DOI: 10.1111/ajt.14504
Abstract: De novo donor‐specific antibodies (dnDSAs) have been associated with reduced graft survival. Tacrolimus (TAC)–based regimens are the most common among immunosuppressive approaches used in in clinical practice today, yet an optimal therapeutic dose to prevent… read more here.
Keywords: tac; risk; time therapeutic; therapeutic range ... See more keywords