Timing is everything: Transcriptional repression is not the default mode for regulating Hedgehog signaling
Sign Up to like & getrecommendations! Published in 2022 at "BioEssays"
DOI: 10.1002/bies.202200139
Abstract: Hedgehog (HH) signaling is a conserved pathway that drives developmental growth and is essential for the formation of most organs. The expression of HH target genes is regulated by a dual switch mechanism where GLI… read more here.
Keywords: hedgehog signaling; default; hedgehog; gli proteins ... See more keywords
Timing is everything: Effects of day and night warming on predator functional traits
Sign Up to like & getrecommendations! Published in 2019 at "Food Webs"
DOI: 10.1016/j.fooweb.2019.e00130
Abstract: Abstract Global mean temperature is increasing; however, when evaluated on a local scale, much of the documented warming is happening asymmetrically, with temperatures increasing either during the day or at night. Yet, most experimental studies… read more here.
Keywords: timing everything; respiration rates; predator; day ... See more keywords
Timing Is Everything: MND1 Regulates Meristem Phase Change in Barley
Sign Up to like & getrecommendations! Published in 2020 at "Plant Physiology"
DOI: 10.1104/pp.20.00648
Abstract: The shoot and inflorescence architecture of grasses are characterized by complex branching patterns, which contribute to the great diversity of this plant clade ([Whipple 2017][1]). During crop domestication, plants were selected for a variety of… read more here.
Keywords: phase change; meristem phase; regulates meristem; timing everything ... See more keywords
Developmental Timing is Everything (Part II): Gating of High Temperature Responses by the Circadian Clock[OPEN]
Sign Up to like & getrecommendations! Published in 2019 at "Plant Cell"
DOI: 10.1105/tpc.19.00632
Abstract: Arabidopsis ( Arabidopsis thaliana ) seedlings exposed to heat stress (>42°C) suffer high lethality rates unless exposed to milder heat (37°C) beforehand. This pre-exposure distinguishes basal from acquired thermotolerance and has been extensively studied over… read more here.
Keywords: timing everything; high temperature; part gating; everything part ... See more keywords
Timing is everything: Survival of Atlantic salmon Salmo salar postsmolts during events of high salmon lice densities
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Applied Ecology"
DOI: 10.1111/1365-2664.13612
Abstract: This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. © 2020 The Authors.… read more here.
Keywords: research; timing everything; survival atlantic; troms norway ... See more keywords
Is timing everything? Bioprosthetic valve fracture in valve‐in‐valve TAVR
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cardiac Surgery"
DOI: 10.1111/jocs.14979
Abstract: We present a challenging case of early bioprosthetic valve degeneration following valve‐in‐valve transcatheter aortic valve replacement and bioprosthetic valve fracture. read more here.
Keywords: valve fracture; valve valve; timing everything; bioprosthetic valve ... See more keywords
Modulating NRF2 in Disease: Timing Is Everything.
Sign Up to like & getrecommendations! Published in 2019 at "Annual review of pharmacology and toxicology"
DOI: 10.1146/annurev-pharmtox-010818-021856
Abstract: The transcription factor nuclear factor erythroid 2 (NF-E2)-related factor 2 (NRF2) is a central regulator of redox, metabolic, and protein homeostasis that intersects with many other signaling cascades. Although the understanding of the complex nature… read more here.
Keywords: disease timing; timing everything; disease; nrf2 disease ... See more keywords
Timing Is Everything: Misincorporation of 8oxodG during Mitosis Is Lethal
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/0008-5472.can-20-1904
Abstract: Exploiting universal cancer vulnerabilities has been used as an approach for developing targeted therapies. In this issue of Cancer Research, Rudd and colleagues show that the dual-functioning inhibitor TH588 potentiates the accumulation of reactive oxygen… read more here.
Keywords: everything misincorporation; mitosis lethal; cancer; misincorporation 8oxodg ... See more keywords
Timing is everything: Developmental changes in the associations between intergroup contact and bias
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Behavioral Development"
DOI: 10.1177/01650254221146409
Abstract: Identifying developmental patterns in intergroup contact and its relation with bias is crucial for improving prevention strategies around intergroup relations. This study applied time-varying effects modeling (TVEM) to examine age-based changes in relations between contact… read more here.
Keywords: contact bias; contact; everything developmental; intergroup contact ... See more keywords