Single quad Mass analyzer coupled UPLC method for impurity profile of Brimonidine tartrate and Timolol maleate: Application in their binary mixture ophthalmic formulation.
Sign Up to like & getrecommendations! Published in 2021 at "Annales pharmaceutiques francaises"
DOI: 10.1016/j.pharma.2021.02.006
Abstract: The main objective of the study is to develop a suitable and rapid UPLC/PDA method by coupling online to Quadrupole Dalton analyzer (QDa), a mass detector for the identification and impurity profiling of Brimonidine Tartrate… read more here.
Keywords: method; timolol maleate; brimonidine tartrate; ophthalmic formulation ... See more keywords
Successful Late Treatment of Orbital Infantile Haemangiomas in Two Teenagers with Topical Transcutaneous Timolol Maleate 0.5% Alone.
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DOI: 10.1055/a-1936-3531
Abstract: We previously described the first successful treatment of deep periocular and, subsequently, orbital infantile haemangiomas (IH) with topical transcutaneous timolol maleate 0.5% (TM 0.5%) alone as the first-line treatment in the acute proliferative phase in infancy.… read more here.
Keywords: proptosis; treatment; case; timolol maleate ... See more keywords
Efficacy and Safety of Introduction Timolol Maleate by Manometer Microneedles among Infantile Hemangioma: A Retrospective Study in China
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DOI: 10.1055/s-0043-57238
Abstract: Abstract Objective The objective of the study was to compare the effective rate, cure rate, adverse reaction rate, and effective time of three methods in the treatment of infantile hemangioma, hoping to provide reference for… read more here.
Keywords: timolol maleate; infantile hemangioma; group; rate ... See more keywords
Full Factorial Design for Development and Validation of a Stability-Indicating RP-HPLC Method for the Estimation of Timolol Maleate in Surfactant-Based Elastic Nano-Vesicular Systems.
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DOI: 10.1093/chromsci/bmab101
Abstract: A novel isocratic stability-indicating chromatographic method was developed, optimized and validated using Design-Expert® following ICH guidelines for the quantification of Timolol maleate (TM). The intrinsic stability of TM was assessed by force degradation studies, which… read more here.
Keywords: stability indicating; method; timolol maleate; surfactant based ... See more keywords
A randomized, controlled, split-face study of topical timolol maleate 0.5% eye drops for the treatment of erythematotelangiectatic rosacea.
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DOI: 10.1111/jocd.14347
Abstract: BACKGROUND Centrofacial erythema associated with telangiectasis is the most common presentation of rosacea, known as erythematotelangiectatic rosacea (ETR). However, successful management of these symptoms remains challenging. AIM The purpose of this study was to evaluate… read more here.
Keywords: face; timolol maleate; maleate eye; topical timolol ... See more keywords
Effect of CYP2D6*4, CYP2D6*10 polymorphisms on the safety of treatment with timolol maleate in patients with glaucoma
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DOI: 10.1515/dmpt-2022-0117
Abstract: Abstract Objectives Timolol maleate is used for the treatment of glaucoma and metabolized by cytochrome CYP2D6 in the liver. The aim of this study was the evaluation of the influence of CYP2D6*4 and CYP2D6*10 gene… read more here.
Keywords: glaucoma; timolol maleate; cyp2d6 cyp2d6; cyp2d6 ... See more keywords
Simultaneous spectrofluorometric analysis of tablets containing hydrochlorothiazide combined with timolol maleate or amiloride hydrochloride
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DOI: 10.2478/acph-2020-0027
Abstract: Abstract Green and sensitive spectrofluorometric methods have been developed and validated for the determination of timolol maleate (TML)/hydrochlorothiazide (HCT) and amiloride hydrochloride (AMH)/hydrochlorothiazide in tablets. The proposed spectrofluorometric procedures were found to be linear in… read more here.
Keywords: hydrochlorothiazide; hct tml; amiloride hydrochloride; timolol maleate ... See more keywords
Development and evaluation of polycaprolactone-based electrospun nanofibers containing timolol maleate as a sustained-release device for treatment of glaucoma: in vivo evaluation in equine eye
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DOI: 10.4103/1735-5362.355196
Abstract: Background and purpose: Prolonging the drug release can be a suitable approach to overcome the challenges related to topical ophthalmic administration of drugs especially the ones prescribed for chronic ailments. The sustained delivery of the… read more here.
Keywords: evaluation; polycaprolactone based; treatment glaucoma; timolol maleate ... See more keywords
Preparation and In-vitro Evaluation of Timolol Maleate Loaded Ocular inserts by using various polymers
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DOI: 10.52711/0974-360x.2023.00208
Abstract: The anatomy physiology and biochemistry of the eye render this organ impervious to foreign substances. Ocusert system was firstly developed in 1975 in the USA. It is a flat, flexible, solid and semisolid device which… read more here.
Keywords: timolol maleate; loaded ocular; maleate loaded; using various ... See more keywords
Effects of timolol maleate eye drops on experimentally dilated cardiomyopathy and healthy rabbits
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DOI: 10.5455/ovj.2021.v11.i3.9
Abstract: Background: Dilated cardiomyopathy (DCM) is the most frequently diagnosed cardiomyopathy in rabbits. Timolol maleate (nonselective beta-blockers), which reduces the heart rate (HR) and blood pressure, has been used for glaucoma. However, this effect has not… read more here.
Keywords: eye drops; maleate eye; dcm models; timolol maleate ... See more keywords