Taking a Swing at TIMP1-Armed Immunosuppressive Astrocytes Unleashes T cell Immunity against Brain Metastases.
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DOI: 10.1158/2159-8290.cd-24-1495
Abstract: Priego and colleagues identify a secreted glycoprotein TIMP1, expressed downstream of the transcription factor STAT3, in a subpopulation of STAT3+ reactive astrocytes as a mediator of immunosuppression in late-stage brain metastases. The STAT3 inhibitor silibinin… read more here.
Keywords: brain metastases; timp1 armed; timp1; taking swing ... See more keywords