Clerodane furanoditerpenoids as the probable cause of toxic hepatitis induced by Tinospora crispa
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DOI: 10.1038/s41598-018-31815-6
Abstract: Tinospora crispa is a popular traditional herbal plant commonly used throughout the world for treatment of various diseases, in particular type 2 diabetes mellitus. We report here a new case of toxic hepatitis in a… read more here.
Keywords: tinospora crispa; crispa; toxic hepatitis; clerodane ... See more keywords
Evaluation of the hepatotoxic potential of Tinospora crispa and its isolated borapetosides B, C and F in a murine model.
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DOI: 10.1055/a-1127-7503
Abstract: The hepatotoxic potential of the methanolic extract of the stems of Tinospora crispa and of its furano-diterpenoid-borapetosides B, C, and F-was investigated in normal and health-compromised mice. Health-compromised condition was established by a single intraperitoneal… read more here.
Keywords: isolated borapetosides; potential tinospora; evaluation hepatotoxic; crispa isolated ... See more keywords
Rearranged clerodane diterpenoid from Tinospora crispa
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DOI: 10.1080/14786419.2019.1633648
Abstract: Abstract A new rearranged clerodane diterpenoid, tinocrispide was isolated from the stems of Tinospora crispa along with thirteen known compounds including eight clerodane diterpenoids. Among the known compounds baenzigeride A, (6S, 9 R)-vomifoliol and steponine are… read more here.
Keywords: clerodane; crispa; clerodane diterpenoid; tinospora crispa ... See more keywords
Network pharmacology integrated molecular dynamics reveals the bioactive compounds and potential targets of Tinospora crispa Linn. as insulin sensitizer
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DOI: 10.1371/journal.pone.0251837
Abstract: Insulin resistance is a metabolic disorder characterized by the decreased response to insulin in muscle, liver, and adipose cells. This condition remains a complex phenomenon that involves several genetic defects and environmental stresses. In the… read more here.
Keywords: insulin sensitizer; pharmacology; molecular dynamics; tinospora crispa ... See more keywords