Tip60 HAT activators as therapeutic modulators for Alzheimer’s disease
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DOI: 10.1038/s41467-025-58496-w
Abstract: Reduced histone acetylation in the brain causes transcriptional dysregulation and cognitive impairment that are key initial steps in Alzheimer’s disease (AD) etiology. Unfortunately, current treatment strategies primarily focus on histone deacetylase inhibition (HDACi) that causes… read more here.
Keywords: alzheimer disease; tip60; acetylation; tip60 hat ... See more keywords