TIPE2 deletion improves the therapeutic potential of adoptively transferred NK cells
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DOI: 10.1136/jitc-2022-006002
Abstract: Background To enhance the efficacy of adoptive NK cell therapy against solid tumors, NK cells must be modified to resist exhaustion in the tumor microenvironment (TME). However, the molecular checkpoint underlying NK cell exhaustion in… read more here.
Keywords: cell; exhaustion; tme; deletion ... See more keywords