Safety and efficacy of prophylactic tirofiban infusion for acute intracranial intraprocedural stent thrombosis
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DOI: 10.1038/s41598-021-00872-9
Abstract: Periprocedural antithrombotic management with glycoprotein IIb/IIIa inhibitors (GPI) for intracranial artery stenting is still controversial. We sought to assess the safety and efficacy of prophylactic tirofiban infusion for acute intracranial intraprocedural stent thrombosis in routine… read more here.
Keywords: tirofiban group; stent thrombosis; safety; prophylactic tirofiban ... See more keywords
Clinical efficacy and safety of tirofiban combined with conventional dual antiplatelet therapy in ACS patients undergoing PCI
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-96606-y
Abstract: Challenges remain for clinicians over balancing the efficacy of active antithrombotic therapy and simultaneous bleeding reduction in patients. The clinical data of 347 patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) were… read more here.
Keywords: group group; group; acs patients; efficacy ... See more keywords
Tirofiban potentiates agonist-induced platelet activation and degranulation, despite effectively inhibiting aggregation
Sign Up to like & getrecommendations! Published in 2022 at "Platelets"
DOI: 10.1080/09537104.2022.2078489
Abstract: Abstract We aimed to investigate the effects of integrin αIIbβ3 inhibitor tirofiban on hallmarks of platelet activation, degranulation, and aggregation during its use to analyze activated but non-complexed platelets via flow cytometry. To do so,… read more here.
Keywords: platelet activation; aggregation; tirofiban; degranulation ... See more keywords
Comparison of Ischemic and Bleeding Events Between Short-Duration Versus Long-Duration Tirofiban Regimens in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000001289
Abstract: Abstract: Tirofiban has been used historically as a bridge to platelet inhibition with clopidogrel in ST-segment myocardial infarction (STEMI) during percutaneous coronary intervention (PCI) to prevent stent thrombosis. However, ticagrelor and prasugrel reach similar levels… read more here.
Keywords: tirofiban; long duration; myocardial infarction; short duration ... See more keywords
Tirofiban in Suspected Left Ventricular Assist Device Pump Thrombosis.
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DOI: 10.1097/mat.0000000000001083
Abstract: Antithrombotic optimization with a glycoprotein IIb/IIIa inhibitor has been used for the treatment of suspected pump thrombosis, but available literature with tirofiban is lacking. This study aims to describe the use of tirofiban for suspected… read more here.
Keywords: tirofiban suspected; pump thrombosis; left ventricular; suspected pump ... See more keywords
Association of Intravenous Tirofiban with Functional Outcomes in Acute Ischemic Stroke Patients with Acute Basilar Artery Occlusion Receiving Endovascular Thrombectomy.
Sign Up to like & getrecommendations! Published in 2022 at "Cerebrovascular diseases"
DOI: 10.1159/000527483
Abstract: INTRODUCTION The aim of this study was to test the hypothesis that intravenous tirofiban improves functional outcomes without promoting the risk of intracranial hemorrhage (ICH) in stroke secondary to basilar artery occlusion (BAO) receiving endovascular… read more here.
Keywords: intravenous tirofiban; tirofiban; endovascular thrombectomy; tirofiban group ... See more keywords
Endovascular Thrombectomy: Tirofiban Increases Bleeding Risk in Acute Stroke Patients
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DOI: 10.1161/strokeaha.118.022919
Abstract: Background and Purpose— This study aimed to explore safety of tirofiban in endovascular treatment of acute ischemic stroke. Methods— Two hundred eighteen ischemic stroke patients receiving endovascular thrombectomy were prospectively recruited, with 94 treated with… read more here.
Keywords: ischemic stroke; thrombectomy tirofiban; stroke patients; endovascular thrombectomy ... See more keywords
Low-Dose Tirofiban Treatment Improves Neurological Deterioration Outcome After Intravenous Thrombolysis.
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DOI: 10.1161/strokeaha.119.026240
Abstract: Background and Purpose- Early use of antiplatelet drugs within 24 hours after intravenous thrombolysis (IVT) has always been a confusing clinical problem. The purpose of this study was to assess the safety and efficacy of… read more here.
Keywords: dose tirofiban; tirofiban treatment; low dose; neurological deterioration ... See more keywords
RESCUE BT 2, a multicenter, randomized, double-blind, double-dummy trial of intravenous tirofiban in acute ischemic stroke: Study rationale and design
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Stroke"
DOI: 10.1177/17474930221122681
Abstract: Background: Tirofiban is a glycoprotein IIb/IIIa receptor inhibitor that has been shown to be effective in the treatment of acute coronary syndromes. However, it remains unknown whether it improves outcomes in patients with acute ischemic… read more here.
Keywords: tirofiban; trial; randomized double; acute ischemic ... See more keywords
Clinical efficacy of tirofiban combined with a Solitaire stent in treating acute ischemic stroke
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DOI: 10.1590/1414-431x20198396
Abstract: This study explores the safety and effect of acute cerebral infarction treatment by microcatheter injection of tirofiban combined with a Solitaire AB stent and/or stent implantation. Emergency cerebral angiograms showing the responsible vascular occlusion of… read more here.
Keywords: combined solitaire; solitaire stent; tirofiban; two groups ... See more keywords
Safety and Efficiency of Low Dose Intra-arterial Tirofiban in Mechanical Thrombectomy During Acute Ischemic Stroke.
Sign Up to like & getrecommendations! Published in 2018 at "Current neurovascular research"
DOI: 10.2174/1567202615666180605104931
Abstract: OBJECTIVE In this study, we aimed to evaluate the safety and efficiency of low dose intra- arterial tirofiban in mechanical thrombectomy of acute ischemic stroke patients to facilitate the reperfusion of distal vessel. METHODS We… read more here.
Keywords: tirofiban group; mechanical thrombectomy; arterial tirofiban; intra arterial ... See more keywords