Structural determinants of dual incretin receptor agonism by tirzepatide
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2116506119
Abstract: Significance Tirzepatide is a dual agonist of the glucose-dependent insulinotropic polypeptide receptor (GIPR) and the glucagon-like peptide-1 receptor (GLP-1R), which are incretin receptors that regulate carbohydrate metabolism. This investigational agent has proven superior to selective… read more here.
Keywords: tirzepatide; determinants dual; dual incretin; structural determinants ... See more keywords
Short-term cost-effectiveness analysis of tirzepatide for the treatment of type 2 diabetes in the United States.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of managed care & specialty pharmacy"
DOI: 10.18553/jmcp.2023.29.3.276
Abstract: BACKGROUND: Tirzepatide is a novel once-a-week dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist that is used as an addition to diet and exercise to improve blood glucose in adults with type 2 diabetes.… read more here.
Keywords: tirzepatide; cost; reduction; treatment ... See more keywords