Articles with "tissue based" as a keyword



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Prediction value with a novel and accurate tissue‐based human papillomavirus detection method in low‐grade squamous intraepithelial lesions

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Published in 2022 at "Cancer Medicine"

DOI: 10.1002/cam4.4634

Abstract: The progression rate from CIN1 to CIN3 is 9.0% and that for invasive cancer is 1.0%. The large majority of CIN1 lesions regress spontaneously, and the treatment of CIN1 is still controversial. read more here.

Keywords: value novel; tissue based; accurate tissue; prediction value ... See more keywords
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The ideal way to design clinical trials and establishment of evidence for human cellular and tissue‐based products in Japan

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Published in 2019 at "Journal of Tissue Engineering and Regenerative Medicine"

DOI: 10.1002/term.2852

Abstract: In Japan, the Pharmaceuticals and Medical Devices (PMD) Act established in 2014 included an additional chapter dedicated to frameworks for human cellular and tissue‐based products. To further evaluate the product considered to have “likely to… read more here.

Keywords: medicine; tissue based; tissue; human cellular ... See more keywords
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A review on the role of tissue-based molecular biomarkers for active surveillance

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Published in 2021 at "World Journal of Urology"

DOI: 10.1007/s00345-021-03610-y

Abstract: Over the last decade, we have seen the emergence of tissue-based genomic prognostic markers that can be used for decision-making regarding the need for treatment. This review provides an up-to-date summary of the relevant literature… read more here.

Keywords: tissue based; review role; role tissue; tissue ... See more keywords
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Immunohistochemistry Innovations for Diagnosis and Tissue-Based Biomarker Detection

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Published in 2019 at "Current Hematologic Malignancy Reports"

DOI: 10.1007/s11899-019-00533-9

Abstract: Immunohistochemistry is an integral technique for tissue-based diagnostics and biomarker detection with broad worldwide adoption. Advances in core chemistries, antibody design, and automation have ushered unprecedented sensitivity, specificity, and reproducibility in immunohistochemistry assays. As a… read more here.

Keywords: tissue based; immunohistochemistry; immunohistochemistry assays; biomarker detection ... See more keywords
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Morphological and tissue-based molecular characterization of oral lesions in patients with COVID-19: A living systematic review

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Published in 2022 at "Archives of Oral Biology"

DOI: 10.1016/j.archoralbio.2022.105374

Abstract: Objective This living systematic review aims to integrate the morphological and tissue-based molecular characterization of oral lesions occurring in individuals infected by COVID-19 (OLICs). Materials and Design This study was performed according to the Preferred… read more here.

Keywords: characterization; living systematic; tissue based; based molecular ... See more keywords
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A tissue-based draft map of the murine MHC class I immunopeptidome

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Published in 2018 at "Scientific Data"

DOI: 10.1038/sdata.2018.157

Abstract: The large array of peptides presented to CD8+ T cells by major histocompatibility complex (MHC) class I molecules is referred to as the MHC class I immunopeptidome. Although the MHC class I immunopeptidome is ubiquitous… read more here.

Keywords: class; tissue based; class immunopeptidome; mhc class ... See more keywords
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MP09-01 GENOMIC HETEROGENEITY IN TISSUE-BASED PROGNOSTIC SIGNATURES FROM PROSTATE BIOPSIES; RESULTS FROM TWO PROSPECTIVE TRIALS

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Published in 2020 at "Journal of Urology"

DOI: 10.1097/ju.0000000000000829.01

Abstract: INTRODUCTION AND OBJECTIVE: Tissue based prognostic signatures have been used in various stages of prostate cancer, including biopsy tissue from men who are deciding between active surveillance versus treatment. Recent studies have suggested that these… read more here.

Keywords: tissue based; prognostic signatures; prospective trials; tissue ... See more keywords

Influence of tissue context on gene prioritization for predicted transcriptome-wide association studies

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Published in 2019 at "Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing"

DOI: 10.1142/9789813279827_0027

Abstract: Transcriptome-wide association studies (TWAS) have recently gained great attention due to their ability to prioritize complex trait-associated genes and promote potential therapeutics development for complex human diseases. TWAS integrates genotypic data with expression quantitative trait… read more here.

Keywords: trait; tissue based; analysis; tissue ... See more keywords
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Abstract WP2: Tissue Based Selection for Large Vessel Occlusion Thrombectomy Leads to Similar Functional Outcomes in Conventional (0-6 Hours) and Extended (>6 Hours) Window

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Published in 2019 at "Stroke"

DOI: 10.1161/str.50.suppl_1.wp2

Abstract: Background: Recent trials have shown benefit of thrombectomy in carefully selected patients in the extended (>6 hours) window. However, it is not clear if the outcomes differ from those undergoing ... read more here.

Keywords: extended hours; tissue based; abstract wp2; thrombectomy ... See more keywords
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Comprehensive molecular profiling of multi-focal prostate cancer and concomitant lymph node metastasis: Implications for tissue-based prognostic biomarkers.

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Published in 2017 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2017.35.15_suppl.5061

Abstract: 5061Background: Current tissue-based prognostic biomarker assays claim that assessment of a single biopsy focus is sufficient to predict disease behavior. We analyzed and compared the genetic profi... read more here.

Keywords: tissue based; multi focal; comprehensive molecular; profiling multi ... See more keywords
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Illustration of temporal evolution in patients with metastatic renal cell carcinoma (mRCC) using both circulating tumor DNA (ctDNA) and tissue-based genomic data.

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Published in 2021 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2021.39.6_suppl.347

Abstract: 347Background: We have previously demonstrated the feasibility of ctDNA assessment in mRCC and preliminarily showed agreement between ctDNA and tissue-based genomic findings (Zengin et al ESMO 2020... read more here.

Keywords: tissue based; based genomic; ctdna; mrcc ... See more keywords