The tissue specific regulation of miR22 expression in the lung and brain by ribosomal protein L29
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-73281-z
Abstract: Endogenous miR22 is associated with a diverse range of biological processes through post-translational modification of gene expression and its deregulation results in various diseases including cancer. Its expression is usually tissue or cell-specific, however, the… read more here.
Keywords: tissue cell; expression; mir22; mir22 expression ... See more keywords
Bioreactor-based advances in plant tissue and cell culture: challenges and prospects
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DOI: 10.1080/07388551.2018.1489778
Abstract: Abstract Bioreactors are engineered systems capable of supporting a biologically active situation for conducting aerobic or anaerobic biochemical processes. Stability, operational ease, improved nutrient uptake capacity, time- and cost-effectiveness, and large quantities of biomass production,… read more here.
Keywords: plant; tissue cell; cell culture; bioreactor ... See more keywords
Drought effects on the tissue- and cell-specific cytokinin activity in poplar
Sign Up to like & getrecommendations! Published in 2018 at "AoB Plants"
DOI: 10.1093/aobpla/plx067
Abstract: Cytokinins are important phytohormones that regulate plant growth. Here we localized cytokinin activities in poplar trees, which are important biomass crops. We demonstrated that even mild drought stress strongly suppresses cytokinin activities in the cambium,… read more here.
Keywords: cytokinin; effects tissue; tissue cell; drought effects ... See more keywords
Decoding multilevel relationships with the human tissue-cell-molecule network
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbac170
Abstract: Understanding the biological functions of molecules in specific human tissues or cell types is crucial for gaining insights into human physiology and disease. To address this issue, it is essential to systematically uncover associations among… read more here.
Keywords: network; cell; molecule network; cell molecule ... See more keywords
EnhancerAtlas 2.0: an updated resource with enhancer annotation in 586 tissue/cell types across nine species
Sign Up to like & getrecommendations! Published in 2020 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkz980
Abstract: Abstract Enhancers are distal cis-regulatory elements that activate the transcription of their target genes. They regulate a wide range of important biological functions and processes, including embryogenesis, development, and homeostasis. As more and more large-scale… read more here.
Keywords: tissue cell; 586 tissue; annotation; enhancer ... See more keywords
COOBoostR: An Extreme Gradient Boosting-Based Tool for Robust Tissue or Cell-of-Origin Prediction of Tumors
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life13010071
Abstract: We here present COOBoostR (https://github.com/SWJ9385/COOBoostR), a computational method designed for the putative prediction of tissue-or cell-of-origin of various cancer types. COOBoostR leverages regional somatic mutation density information and chromatin mark features to be applied to… read more here.
Keywords: somatic mutation; cell; cell origin; tissue cell ... See more keywords
Mouse aging cell atlas analysis reveals global and cell type-specific aging signatures
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DOI: 10.7554/elife.62293
Abstract: Aging is associated with complex molecular and cellular processes that are poorly understood. Here we leveraged the Tabula Muris Senis single-cell RNA-seq data set to systematically characterize gene expression changes during aging across diverse cell… read more here.
Keywords: mouse aging; specific aging; tissue cell; cell types ... See more keywords