Recreating Physiological Environments In Vitro: Design Rules for Microfluidic-Based Vascularized Tissue Constructs.
Sign Up to like & getrecommendations! Published in 2020 at "Small"
DOI: 10.1002/smll.201905055
Abstract: Vascularization of engineered tissue constructs remains one of the greatest unmet challenges to mimicking the native tissue microenvironment in vitro. The main obstacle is recapitulating the complexity of the physiological environment while providing simplicity in… read more here.
Keywords: microfluidic based; microenvironment; recreating physiological; tissue ... See more keywords
Three-dimensional fabrication of thick and densely populated soft constructs with complex and actively perfused channel network.
Sign Up to like & getrecommendations! Published in 2018 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2017.10.047
Abstract: One of the fundamental steps needed to design functional tissues and, ultimately organs is the ability to fabricate thick and densely populated tissue constructs with controlled vasculature and microenvironment. To date, bioprinting methods have been… read more here.
Keywords: network; tissue; thick densely; geometry ... See more keywords
Engineering of tissue constructs using coaxial bioprinting
Sign Up to like & getrecommendations! Published in 2021 at "Bioactive Materials"
DOI: 10.1016/j.bioactmat.2020.08.020
Abstract: Bioprinting is a rapidly developing technology for the precise design and manufacture of tissues in various biological systems or organs. Coaxial extrusion bioprinting, an emergent branch, has demonstrated a strong potential to enhance bioprinting's engineering… read more here.
Keywords: coaxial bioprinting; bioprinting engineering; tissue; tissue constructs ... See more keywords
Direct 3D bioprinting of prevascularized tissue constructs with complex microarchitecture.
Sign Up to like & getrecommendations! Published in 2017 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2017.01.042
Abstract: Living tissues rely heavily on vascular networks to transport nutrients, oxygen and metabolic waste. However, there still remains a need for a simple and efficient approach to engineer vascularized tissues. Here, we created prevascularized tissues… read more here.
Keywords: bioprinting prevascularized; prevascularized tissue; tissue; direct bioprinting ... See more keywords
3D printed nanocomposites for tailored cardiovascular tissue constructs: A minireview
Sign Up to like & getrecommendations! Published in 2021 at "Materialia"
DOI: 10.1016/j.mtla.2021.101184
Abstract: Abstract Cardiovascular diseases (CVD) with escalating death rates pose one of the greatest threats to global health and well-being. Thus, developing effective interventions to combat CVD are of critical importance. 3D printing fabrication of engineered… read more here.
Keywords: nanocomposites tailored; constructs minireview; tailored cardiovascular; printed nanocomposites ... See more keywords
Biomimetic bioinks of nanofibrillar polymeric hydrogels for 3D bioprinting
Sign Up to like & getrecommendations! Published in 2021 at "Nano Today"
DOI: 10.1016/j.nantod.2021.101180
Abstract: Abstract 3D bioprinting is a rapidly emerging technology to manufacture biological tissue constructs that more closely recapitulate physiological features of native tissue, and thus facilitates innovative research directions to revolutionize the fundamental understanding and practical… read more here.
Keywords: polymeric hydrogels; biomimetic bioinks; nanofibrillar polymeric; nanofibrillar hydrogels ... See more keywords
Tunable and Compartmentalized Multimaterial Bioprinting for Complex Living Tissue Constructs.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c12585
Abstract: Recapitulating inherent heterogeneity and complex microarchitectures within confined print volumes for developing implantable constructs that could maintain their structure in vivo has remained challenging. Here, we present a combinational multimaterial and embedded bioprinting approach to… read more here.
Keywords: tunable compartmentalized; colloidal gels; tissue constructs; compartmentalized multimaterial ... See more keywords
Hydrogel microfibers with perfusable folded channels for tissue constructs with folded morphology
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DOI: 10.1039/c8ra04192j
Abstract: Fiber-based materials with microchannels have drawn considerable attention in recent years owing to their ability to mimic intrinsic morphologies of living tissues. Folded morphologies, which are common in vivo, such as in skeletal muscle capillaries… read more here.
Keywords: constructs folded; perfusable folded; hydrogel microfibers; tissue ... See more keywords
Fabrication of vascularized tissue constructs under chemically defined culture conditions.
Sign Up to like & getrecommendations! Published in 2020 at "Biofabrication"
DOI: 10.1088/1758-5090/aba0c2
Abstract: Three-dimensional (3D) biofabrication techniques that enable the production of multicellular tissue equivalents for applications in basic biology, drug screening and regenerative medicne. Fabrication of these tissue constructs with in-built microvasculature enables recapitulation of the biological… read more here.
Keywords: hesc; fabrication vascularized; tissue; culture ... See more keywords
Biodegradable Inks in Indirect Three-Dimensional Bioprinting for Tissue Vascularization
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.856398
Abstract: Mature vasculature is important for the survival of bioengineered tissue constructs, both in vivo and in vitro; however, the fabrication of fully vascularized tissue constructs remains a great challenge in tissue engineering. Indirect three-dimensional (3D)… read more here.
Keywords: indirect three; vascularization; tissue constructs; tissue ... See more keywords
Biomimetic cardiac tissue chip and murine arteriovenous fistula models for recapitulating clinically relevant cardiac remodeling under volume overload conditions
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2023.1101622
Abstract: Cardiovascular events are the primary cause of death among dialysis patients. While arteriovenous fistulas (AVFs) are the access of choice for hemodialysis patients, AVF creation can lead to a volume overload (VO) state in the… read more here.
Keywords: volume overload; tissue constructs; mice; cardiac tissue ... See more keywords