Neonatal Tissue-derived Extracellular Vesicle Therapy (NEXT): A Potent Strategy for Precision Regenerative Medicine.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced materials"
DOI: 10.1002/adma.202300602
Abstract: Extracellular vesicle (EV)-based therapies have emerged as a promising means in regenerative medicine. However, the conventional EV therapy strategy (using EVs from a single type of cultured cell) displays some limitations, such as inefficient EV… read more here.
Keywords: neonatal tissue; tissue derived; strategy; tissue ... See more keywords
Expansion of adipose tissue‐derived stromal cells at “physiologic” hypoxia attenuates replicative senescence
Sign Up to like & getrecommendations! Published in 2017 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3267
Abstract: Multipotent mesenchymal stromal cells are considered as a perspective tool in cell therapy and regenerative medicine. Unfortunately, autologous cell therapy does not always provide positive outcomes in elder donors, perhaps as a result of the… read more here.
Keywords: replicative senescence; stromal cells; senescence; adipose tissue ... See more keywords
Adipose tissue‐derived mesenchymal stem cells and keratinocytes co‐culture on gelatin/chitosan/β‐glycerol phosphate nanoscaffold in skin regeneration
Sign Up to like & getrecommendations! Published in 2019 at "Cell Biology International"
DOI: 10.1002/cbin.11119
Abstract: Using cell‐based engineered skin is an emerging strategy for treating difficult‐to‐heal wounds. To date, much endeavor has been devoted to the fabrication of appropriate scaffolds with suitable biomechanical properties to support cell viability and growth… read more here.
Keywords: derived mesenchymal; gelatin chitosan; tissue derived; adipose tissue ... See more keywords
Effect of allogeneic adipose tissue‐derived mesenchymal stromal cell treatment in chronic ischaemic heart failure with reduced ejection fraction – the SCIENCE trial
Sign Up to like & getrecommendations! Published in 2023 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.2772
Abstract: The aim of the SCIENCE trial was to investigate whether a single treatment with direct intramyocardial injections of adipose tissue‐derived mesenchymal stromal cells (CSCC_ASCs) was safe and improved cardiac function in patients with chronic ischaemic… read more here.
Keywords: tissue derived; heart failure; science trial; adipose tissue ... See more keywords
Adipose tissue‐derived stem cells inhibit hypertrophic scar (HS) fibrosis via p38/MAPK pathway
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27689
Abstract: The current study was designed to investigate the effects and underlying mechanisms of adipose tissue‐derived stem cells (ADSCs) on hypertrophic scar (HS) fibrosis. read more here.
Keywords: hypertrophic scar; derived stem; scar fibrosis; adipose tissue ... See more keywords
Transposon-mediated glial cell line-derived neurotrophic factor overexpression in human adipose tissue-derived mesenchymal stromal cells: A potential approach for neuroregenerative medicine?
Sign Up to like & getrecommendations! Published in 2022 at "Journal of tissue engineering and regenerative medicine"
DOI: 10.1002/term.3296
Abstract: Glial cell line-derived neurotrophic factor (GDNF) has neuroprotective effects and may be a promising candidate for regenerative strategies focusing on neurodegenerative diseases. As GDNF cannot cross the blood-brain barrier to potentially regenerate damaged brain areas,… read more here.
Keywords: tissue derived; medicine; overexpression; adipose tissue ... See more keywords
High-Dimensional Analysis of Circulating and Tissue-Derived Myeloid-Derived Suppressor Cells from Patients with Glioblastoma.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1060-2_13
Abstract: We will first describe analysis of MDSC subsets from patient tumors with multicolor flow cytometry. The key components of this methodology are to obtain viable single cell suspensions and eliminate red blood cell contamination. read more here.
Keywords: high dimensional; analysis; analysis circulating; circulating tissue ... See more keywords
Evaluation of Extracellular Vesicles from Adipose Tissue-Derived Mesenchymal Stem Cells in Primary Human Chondrocytes from Patients with Osteoarthritis.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1225-5_15
Abstract: Adipose tissue-derived mesenchymal stem cells (AD-MSCs) offer great therapeutic potential for osteoarthritis (OA) treatment. Recent investigations have revealed the contribution of extracellular vesicles (EVs) to AD-MSC actions. Here, we describe a method to study the… read more here.
Keywords: extracellular vesicles; derived mesenchymal; tissue derived; adipose tissue ... See more keywords
Tissue-derived scaffolds and cells for articular cartilage tissue engineering: characteristics, applications and progress
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DOI: 10.1007/s00441-017-2772-z
Abstract: There are many factors to consider in the field of tissue engineering. For articular cartilage repair, this includes seed cells, scaffolds and chondrotrophic hormones. This review primarily focuses on the seed cells and scaffolds. Extracellular… read more here.
Keywords: seed; tissue; derived scaffolds; tissue engineering ... See more keywords
Protein disulfide isomerase family A member 3 expression is upregulated in tissue-derived extracellular vesicles in oral lichen planus and oral lichenoid lesions.
Sign Up to like & getrecommendations! Published in 2022 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2022.105390
Abstract: OBJECTIVES The aim of this study was to identify the tissue-derived extracellular vesicles immunogen involved in the pathogenesis of oral lichen planus (OLP) and its variation oral lichenoid lesions (OLL). DESIGN Six pooled tissue-derived extracellular… read more here.
Keywords: oral lichen; oral lichenoid; tissue derived; derived extracellular ... See more keywords
Upregulated tumor necrosis factor-α transcriptome and proteome in adipose tissue-derived mesenchymal stem cells from pigs with metabolic syndrome.
Sign Up to like & getrecommendations! Published in 2020 at "Cytokine"
DOI: 10.1016/j.cyto.2020.155080
Abstract: INTRODUCTION Mesenchymal stem cells (MSCs) have endogenous reparative properties, and may constitute an exogenous therapeutic intervention in patients with chronic kidney disease. The microenvironment of metabolic syndrome (MetS) induces fat inflammation, with abundant expression of… read more here.
Keywords: tissue derived; adipose tissue; factor; stem cells ... See more keywords