Adipose tissue dysfunction is associated with low levels of the novel Palmitic Acid Hydroxystearic Acids
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-34113-3
Abstract: Adipose tissue dysfunction is considered an important contributor to systemic insulin resistance and Type 2 diabetes (T2D). Recently, a novel family of endogenous lipids, palmitic acid hydroxy stearic acids (PAHSAs), was discovered. These have anti-diabetic… read more here.
Keywords: palmitic acid; tissue dysfunction; tissue; dysfunction associated ... See more keywords
Physiological Aging: Links Among Adipose Tissue Dysfunction, Diabetes, and Frailty.
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DOI: 10.1152/physiol.00012.2016
Abstract: Advancing age is associated with progressive declines in physiological function that lead to overt chronic disease, frailty, and eventual mortality. Importantly, age-related physiological changes occur in cellularity, insulin-responsiveness, secretory profiles, and inflammatory status of adipose… read more here.
Keywords: tissue dysfunction; age; tissue; physiological aging ... See more keywords
Unravelling the genetic landscape of cervical insufficiency: Insights into connective tissue dysfunction and hormonal pathways
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DOI: 10.1371/journal.pone.0310718
Abstract: Background The intricate molecular pathways and genetic factors that underlie the pathophysiology of cervical insufficiency (CI) remain largely unknown and understudied. Methods We sequenced exomes from 114 patients in Latvia and Lithuania, diagnosed with a… read more here.
Keywords: tissue dysfunction; connective tissue; cervical insufficiency; tissue ... See more keywords
Replication of Integrative Data Analysis for Adipose Tissue Dysfunction, Low-Grade Inflammation, Postprandial Responses and OMICs Signatures in Symptom-Free Adults
Sign Up to like & getrecommendations! Published in 2021 at "Biology"
DOI: 10.3390/biology10121342
Abstract: Simple Summary There is an alarming increase of cardiovascular disease (CVD) and type 2 diabetes (T2D) in Mexican nationals and Mexican Americans. Studying adipose tissue (AT) dysfunction and early biomarkers of cardiovascular and immunometabolic risk… read more here.
Keywords: dysfunction; medicine; symptom free; adipose tissue ... See more keywords
Adipose Tissue Dysfunction and Obesity-Related Male Hypogonadism
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158194
Abstract: Obesity is a chronic illness associated with several metabolic derangements and comorbidities (i.e., insulin resistance, leptin resistance, diabetes, etc.) and often leads to impaired testicular function and male subfertility. Several mechanisms may indeed negatively affect… read more here.
Keywords: male hypogonadism; adipose tissue; obesity; tissue dysfunction ... See more keywords
Adipose Tissue Dysfunction Related to Climate Change and Air Pollution: Understanding the Metabolic Consequences
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms25147849
Abstract: Obesity, a global pandemic, poses a major threat to healthcare systems worldwide. Adipose tissue, the energy-storing organ during excessive energy intake, functions as a thermoregulator, interacting with other tissues to regulate systemic metabolism. Specifically, brown… read more here.
Keywords: tissue dysfunction; obesity; adipose tissue; climate change ... See more keywords