Safety and efficacy of G2-S16 dendrimer as microbicide in healthy human vaginal tissue explants
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Nanobiotechnology"
DOI: 10.1186/s12951-022-01350-8
Abstract: Background The absence of an effective treatment and vaccine in HIV-1 pandemic place preventive strategies such as safety and effective microbicide development as a central therapeutic approach to control HIV-1 pandemic nowadays. Results Studies of… read more here.
Keywords: microbicide; vaginal tissue; s16 dendrimer; tissue explants ... See more keywords
Seminal plasma induces inflammation and enhances HIV-1 replication in human cervical tissue explants
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1006402
Abstract: The most immediate and evident effect of mucosal exposure to semen in vivo is a local release of proinflammatory mediators accompanied by an influx of leukocytes into the female genital mucosa (FGM). The implication of… read more here.
Keywords: hiv replication; tissue; seminal plasma; tissue explants ... See more keywords
Proteomic Assessment of Extracellular Vesicles from Canine Tissue Explants as a Pipeline to Identify Molecular Targets in Osteosarcoma: PSMD14/Rpn11 as a Proof of Principle
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DOI: 10.3390/ijms23063256
Abstract: Osteosarcoma (OS) is a highly malignant bone tumour that has seen little improvement in treatment modalities in the past 30 years. Understanding what molecules contribute to OS biology could aid in the discovery of novel… read more here.
Keywords: molecular targets; pipeline; extracellular vesicles; psmd14 rpn11 ... See more keywords
Anti-Inflammatory Effects of Pomegranate Peel Extracts on In Vitro Human Intestinal Caco-2 Cells and Ex Vivo Porcine Colonic Tissue Explants
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DOI: 10.3390/nu11030548
Abstract: The aim of this study was to determine the anti-inflammatory potential of pomegranate peel extracts (PPE) prepared from waste material of pomegranate juice production both in vitro on Caco-2 cells and ex vivo using porcine… read more here.
Keywords: anti inflammatory; tissue explants; colonic tissue; caco cells ... See more keywords