Validation of tissue factor pathway inhibitor 2 as a specific biomarker for preoperative prediction of clear cell carcinoma of the ovary
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Clinical Oncology"
DOI: 10.1007/s10147-021-01914-y
Abstract: Tissue factor pathway inhibitor 2 (TFPI2) is a novel serum biomarker that discriminates ovarian clear cell carcinoma (CCC) from borderline ovarian tumors (BOTs) and non-clear cell epithelial ovarian cancers (EOCs). Here, we examined the performance… read more here.
Keywords: ccc; ca125; tfpi2; tissue factor ... See more keywords
Influence of tissue factor polymorphisms (603A>G and 5466A>G) on plasma tissue factor levels and their impact on deep vein thrombosis risk in young Indian population
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Thrombosis and Thrombolysis"
DOI: 10.1007/s11239-018-1666-6
Abstract: Deep vein thrombosis (DVT) is multifactorial disorder and well known to cause substantial morbidity and mortality. There is sparse data in the Asian population, particularly India regarding association of tissue factor (TF) gene single nucleotide… read more here.
Keywords: tissue factor; 603a 5466a; factor; thrombosis ... See more keywords
Anti-tissue factor pathway inhibitor (TFPI) therapy: a novel approach to the treatment of haemophilia
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Hematology"
DOI: 10.1007/s12185-018-2548-6
Abstract: Novel approaches to the treatment of haemophilia are needed due to the limitations of the current standard of care, factor replacement therapy. Aspirations include lessening the treatment burden and effectively preventing joint damage. Treating haemophilia… read more here.
Keywords: inhibitor; treatment; tissue factor; factor ... See more keywords
Progress Curve Analysis of Microtitre Plate Plasma Clotting Assays. Assessment of Tissue Factor Levels.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2020.114060
Abstract: MTP plasma clotting assays monitor the time course of fibrin formation in re-calcified plasma by absorbance measurements and are increasingly used as alternatives to traditional one-point clot time assays employed in clinical laboratories to detect… read more here.
Keywords: clot; clotting assays; factor levels; plasma clotting ... See more keywords
Tissue factor pathway inhibitor attenuates ER stress-induced inflammation in human M2-polarized macrophages.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.07.070
Abstract: Endoplasmic reticulum (ER) stress has been shown to play a key role during the initiation and clinical progression of the cardiovascular diseases, such as atherosclerosis. We have recently shown that expression of tissue factor pathway… read more here.
Keywords: inhibitor; tissue factor; pathway; stress ... See more keywords
Increasing the sensitivity of the human microvesicle tissue factor activity assay.
Sign Up to like & getrecommendations! Published in 2019 at "Thrombosis research"
DOI: 10.1016/j.thromres.2019.07.011
Abstract: INTRODUCTION The TF-FVIIa complex is the primary activator of coagulation. Elevated levels of microvesicle (MV) bearing tissue factor (TF)-dependent procoagulant activity are detectable in patients with an increased risk of thrombosis. Several methods have been… read more here.
Keywords: microvesicle; activity; tissue factor; sensitivity ... See more keywords
Tissue Factor and Risk of Complications After Kidney Transplantation.
Sign Up to like & getrecommendations! Published in 2020 at "Transplantation proceedings"
DOI: 10.1016/j.transproceed.2020.01.092
Abstract: OBJECTIVE Tissue factor (TF) is a membrane component of many cells and a strong activator of blood coagulation. Damage to the cells induces an increase in its expression and concentration in blood plasma. The injury… read more here.
Keywords: vein; blood; tissue factor; kidney ... See more keywords
COLCHICINE EXERTS ANTITHROMBOTIC PROPERTIES IN OXLDL-TREATED ENDOTHELIAL CELLS VIA INHIBITION OF TISSUE FACTOR EXPRESSION AND ACTIVITY
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(17)35424-4
Abstract: Background: Tissue factor (TF) exposure is the key trigger of thrombus formation. Oxidized low-density lipoproteins (oxLDL) induce TF in endothelial cells (ECs), suggesting that oxLDL may act locally promoting thrombosis in atherosclerotic lesions. Colchicine (COL)… read more here.
Keywords: exerts antithrombotic; endothelial cells; tissue factor; colchicine exerts ... See more keywords
Molecular imaging using an anti-human tissue factor monoclonal antibody in an orthotopic glioma xenograft model
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-12563-5
Abstract: Nuclear medicine examinations for imaging gliomas have been introduced into clinical practice to evaluate the grade of malignancy and determine sampling locations for biopsies. However, these modalities have some limitations. Tissue factor (TF) is overexpressed… read more here.
Keywords: using anti; anti human; tissue factor; monoclonal antibody ... See more keywords
Adipocytes express tissue factor and FVII and are procoagulant in a TF/FVIIa-dependent manner
Sign Up to like & getrecommendations! Published in 2019 at "Upsala Journal of Medical Sciences"
DOI: 10.1080/03009734.2019.1645248
Abstract: Abstract Background: Tissue factor (TF) combined with its ligand FVII initiates blood coagulation and intracellular signaling. Obese and type 2 diabetic subjects have increased TF expression in their adipose tissue and an increased risk for… read more here.
Keywords: fvii; fviia; fviia dependent; tissue factor ... See more keywords
Contribution of allosteric disulfide in the structural regulation of membrane-bound tissue factor–factor VIIa binary complex
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2018.1526118
Abstract: Abstract Two distinct populations, active and cryptic forms of tissue factor (TF), reside on the cell surface. Apart from phospholipid contribution, various models have been introduced to explain decryption/encryption of TF. The proposed model, the… read more here.
Keywords: factor viia; disulfide bond; membrane bound; bond ... See more keywords