Articles with "tissue microarray" as a keyword



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Application of Tissue Microarray in Esophageal Adenocarcinoma.

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Published in 2018 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-7734-5_10

Abstract: Tissue microarray technology could allow immunohistochemical staining or in situ hybridization on hundreds of different tissue samples simultaneously. It allows faster analysis and considerably reducing costs incurred in staining. The technique also provides a high-throughput… read more here.

Keywords: microarray esophageal; application tissue; esophageal adenocarcinoma; tissue ... See more keywords
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Making a Tissue Microarray.

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Published in 2019 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-8935-5_27

Abstract: Tissue microarray (TMA) is a widely used, high-throughput, cost-effective, and tissue and reagent-conserving method of performing molecular analysis. Multiple donor tissue cores are procured and transferred into a recipient TMA block for simultaneous differential and… read more here.

Keywords: making tissue; tissue; biology; tma ... See more keywords
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Tissue microarrays – translational biomarker research in the fast lane

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Published in 2018 at "Expert Review of Molecular Diagnostics"

DOI: 10.1080/14737159.2018.1522252

Abstract: The tissue microarray (TMA) method allows high-throughput biomarker analysis of large cohorts of tissue samples. The method is used for diagnostic profiling, evaluation of predictive or prognostic biomarkers, detection of disease biology (for example, pathway… read more here.

Keywords: research; tissue microarrays; biomarker; pathology ... See more keywords
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Methods for preparing tissue microarray slides using xenografts with different levels of HER2 expression to standardize HER2 detection

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Published in 2022 at "Pathology International"

DOI: 10.1111/pin.13288

Abstract: Gene amplification and protein overexpression of human epidermal growth factor receptor type 2 (HER2) are specific targets for HER2‐targeting drugs in breast, gastric, salivary gland, and colorectal cancers. The histopathological determination of HER2 status is… read more here.

Keywords: tissue microarray; her2; her2 detection;
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An introduction of an easy-operating and economical technique for tissue microarray preparation

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Published in 2019 at "Journal of Clinical Pathology"

DOI: 10.1136/jclinpath-2019-206142

Abstract: Aim Tissue microarray (TMA) is a powerful and effective tool for in situ tissue analysis. However, manual TMA construction methods showed varied qualities. This study aimed to raise a standardised TMA preparation technique that can… read more here.

Keywords: block; tissue; tma; tissue microarray ... See more keywords
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Analysis of LINC01314 and miR-96 Expression in Colorectal Cancer Patients via Tissue Microarray-Based Fluorescence In Situ Hybridization

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Published in 2022 at "Disease Markers"

DOI: 10.1155/2022/5378963

Abstract: Methods A tissue microarray (TMA) containing 76 individual colorectal tumor samples and 28 adjacent normal samples was constructed, and the expression levels of LINC01314 and miR-96 were detected by fluorescence in situ hybridization. Results The… read more here.

Keywords: linc01314 mir; situ hybridization; tissue microarray; fluorescence situ ... See more keywords
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Tissue microarray staining reveals PLD1 and Sp1 have a collaborative, pro-tumoral effect in patients with osteosarcomas

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Published in 2017 at "Oncotarget"

DOI: 10.18632/oncotarget.20605

Abstract: It has been reported that phospholipase D1 (PLD1) - a key enzyme involved in lipid metabolism - is important for the initiation and progression of various human solid cancers; however, its biological significance and regulation… read more here.

Keywords: microarray staining; pld1 sp1; tissue; patients osteosarcomas ... See more keywords
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Correlation of nuclear pIGF-1R/IGF-1R and YAP/TAZ in a tissue microarray with outcomes in osteosarcoma patients

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Published in 2022 at "Oncotarget"

DOI: 10.18632/oncotarget.28215

Abstract: Osteosarcoma (OS) is a genetically diverse bone cancer that lacks a consistent targetable mutation. Recent studies suggest the IGF/PI3K/mTOR pathway and YAP/TAZ paralogs regulate cell fate and proliferation in response to biomechanical cues within the… read more here.

Keywords: nuclear pigf; taz; yap taz; tissue microarray ... See more keywords
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Inhibin Alpha Expression in Human Tumors: A Tissue Microarray Study on 12,212 Tumors

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Published in 2022 at "Biomedicines"

DOI: 10.3390/biomedicines10102507

Abstract: As a result of its expression in corresponding normal cell types, inhibin alpha (INHA) is used as an immunohistochemical marker for adrenocortical neoplasms and testicular or ovarian sex cord stromal tumors. However, other tumors can… read more here.

Keywords: inhibin alpha; cell; tissue microarray; inha ... See more keywords
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Tissue Microarray Analyses Suggest Axl as a Predictive Biomarker in HPV-Negative Head and Neck Cancer

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Published in 2022 at "Cancers"

DOI: 10.3390/cancers14071829

Abstract: Simple Summary Despite many efforts, no predictive biomarkers that could guide clinical decision making and personalized treatment have been established for patients with head and neck squamous cell carcinoma. We propose that high expression of… read more here.

Keywords: hpv negative; tissue microarray; head neck; expression ... See more keywords
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CD44, PDL1, and ATG7 Expression in Laryngeal Squamous Cell Carcinomas with Tissue Microarray (TMA) Technique: Evaluation of the Potential Prognostic and Predictive Roles

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Published in 2023 at "Cancers"

DOI: 10.3390/cancers15092461

Abstract: Simple Summary We are going to highlight new prognostic and predictive factors, CD44, PDL1, and ATG7, in surgical samples from patients with laryngeal squamous cell carcinoma (LSCC). Immunohistochemical analysis with primary antibodies anti-CD44, PD-L1 and… read more here.

Keywords: cd44 pdl1; tissue microarray; squamous cell; pdl1 atg7 ... See more keywords