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Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7734-5_10
Abstract: Tissue microarray technology could allow immunohistochemical staining or in situ hybridization on hundreds of different tissue samples simultaneously. It allows faster analysis and considerably reducing costs incurred in staining. The technique also provides a high-throughput…
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Keywords:
microarray esophageal;
application tissue;
esophageal adenocarcinoma;
tissue ... See more keywords
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Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8935-5_27
Abstract: Tissue microarray (TMA) is a widely used, high-throughput, cost-effective, and tissue and reagent-conserving method of performing molecular analysis. Multiple donor tissue cores are procured and transferred into a recipient TMA block for simultaneous differential and…
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Keywords:
making tissue;
tissue;
biology;
tma ... See more keywords
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Published in 2018 at "Expert Review of Molecular Diagnostics"
DOI: 10.1080/14737159.2018.1522252
Abstract: The tissue microarray (TMA) method allows high-throughput biomarker analysis of large cohorts of tissue samples. The method is used for diagnostic profiling, evaluation of predictive or prognostic biomarkers, detection of disease biology (for example, pathway…
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Keywords:
research;
tissue microarrays;
biomarker;
pathology ... See more keywords
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Published in 2022 at "Pathology International"
DOI: 10.1111/pin.13288
Abstract: Gene amplification and protein overexpression of human epidermal growth factor receptor type 2 (HER2) are specific targets for HER2‐targeting drugs in breast, gastric, salivary gland, and colorectal cancers. The histopathological determination of HER2 status is…
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Keywords:
tissue microarray;
her2;
her2 detection;
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Published in 2019 at "Journal of Clinical Pathology"
DOI: 10.1136/jclinpath-2019-206142
Abstract: Aim Tissue microarray (TMA) is a powerful and effective tool for in situ tissue analysis. However, manual TMA construction methods showed varied qualities. This study aimed to raise a standardised TMA preparation technique that can…
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Keywords:
block;
tissue;
tma;
tissue microarray ... See more keywords
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Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/5378963
Abstract: Methods A tissue microarray (TMA) containing 76 individual colorectal tumor samples and 28 adjacent normal samples was constructed, and the expression levels of LINC01314 and miR-96 were detected by fluorescence in situ hybridization. Results The…
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Keywords:
linc01314 mir;
situ hybridization;
tissue microarray;
fluorescence situ ... See more keywords
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Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.20605
Abstract: It has been reported that phospholipase D1 (PLD1) - a key enzyme involved in lipid metabolism - is important for the initiation and progression of various human solid cancers; however, its biological significance and regulation…
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Keywords:
microarray staining;
pld1 sp1;
tissue;
patients osteosarcomas ... See more keywords
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Published in 2022 at "Oncotarget"
DOI: 10.18632/oncotarget.28215
Abstract: Osteosarcoma (OS) is a genetically diverse bone cancer that lacks a consistent targetable mutation. Recent studies suggest the IGF/PI3K/mTOR pathway and YAP/TAZ paralogs regulate cell fate and proliferation in response to biomechanical cues within the…
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Keywords:
nuclear pigf;
taz;
yap taz;
tissue microarray ... See more keywords
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Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10102507
Abstract: As a result of its expression in corresponding normal cell types, inhibin alpha (INHA) is used as an immunohistochemical marker for adrenocortical neoplasms and testicular or ovarian sex cord stromal tumors. However, other tumors can…
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Keywords:
inhibin alpha;
cell;
tissue microarray;
inha ... See more keywords
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Published in 2022 at "Cancers"
DOI: 10.3390/cancers14071829
Abstract: Simple Summary Despite many efforts, no predictive biomarkers that could guide clinical decision making and personalized treatment have been established for patients with head and neck squamous cell carcinoma. We propose that high expression of…
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Keywords:
hpv negative;
tissue microarray;
head neck;
expression ... See more keywords
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Published in 2023 at "Cancers"
DOI: 10.3390/cancers15092461
Abstract: Simple Summary We are going to highlight new prognostic and predictive factors, CD44, PDL1, and ATG7, in surgical samples from patients with laryngeal squamous cell carcinoma (LSCC). Immunohistochemical analysis with primary antibodies anti-CD44, PD-L1 and…
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Keywords:
cd44 pdl1;
tissue microarray;
squamous cell;
pdl1 atg7 ... See more keywords