Tissue microenvironment dictates inflammation and disease activity in rheumatoid arthritis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the Formosan Medical Association = Taiwan yi zhi"
DOI: 10.1016/j.jfma.2022.01.026
Abstract: The recent advance in treatments for rheumatoid arthritis (RA) has significantly improved the prognosis of RA patients. However, these novel therapies do not work well for all RA patients. The unmet need suggests that the… read more here.
Keywords: tissue; tissue microenvironment; rheumatoid arthritis; activity ... See more keywords
SAT0332 A high-dimensional approach to dissecting the role of the tissue microenvironment in shaping the immune response in psoriatic arthritis
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.6115
Abstract: Background Psoriasis (Ps) currently inflicts 2%–3% of the population globally and one-third of patients have psoriatic arthritis (PsA). Up to 30% of PsA patients with active psoriasis (Ps) do not respond adequately to any treatment.… read more here.
Keywords: immune response; psa patients; tissue microenvironment; response ... See more keywords
Abstract 300: Mechanisms of growth hormone action in the aging tissue microenvironment
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-300
Abstract: The aging tissue microenvironment undergoes progressive changes enabling age-related pathologies. Senescent cells increase with age, and the secretome released from senescence cells (SASP) affects neighboring cells, often promoting proliferation, tissue inflammation, angiogenesis, and, depending on… read more here.
Keywords: growth hormone; tissue microenvironment; aging tissue; tissue ... See more keywords
A Dynamic Transcriptome Map of Different Tissue Microenvironment Cells Identified During Gastric Cancer Development Using Single-Cell RNA Sequencing
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.728169
Abstract: Gastric cancer (GC) development trends have identified multiple processes ranging from inflammation to carcinogenesis, however, key pathogenic mechanisms remain unclear. Tissue microenvironment (TME) cells are critical for the progression of malignant tumors. Here, we generated… read more here.
Keywords: gastric cancer; tissue microenvironment; dynamic transcriptome; cell ... See more keywords
The hypoxic tissue microenvironment as a driver of mucosal inflammatory resolution
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1124774
Abstract: On the backdrop of all acute inflammatory processes lies the activation of the resolution response. Recent years have witnessed an emerging interest in defining molecular factors that influence the resolution of inflammation. A keystone feature… read more here.
Keywords: tissue microenvironment; mucosal inflammatory; resolution; inflammatory resolution ... See more keywords
TGF-β and the Tissue Microenvironment: Relevance in Fibrosis and Cancer
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19051294
Abstract: Transforming growth factor-β (TGF-β) is a cytokine essential for the induction of the fibrotic response and for the activation of the cancer stroma. Strong evidence suggests that a strong cross-talk exists among TGF-β and the… read more here.
Keywords: cancer; tissue microenvironment; tgf; tgf tissue ... See more keywords
Mast Cells as a Potential Target of Molecular Hydrogen in Regulating the Local Tissue Microenvironment
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceuticals"
DOI: 10.3390/ph16060817
Abstract: Knowledge of the biological effects of molecular hydrogen (H2), hydrogen gas, is constantly advancing, giving a reason for the optimism in several healthcare practitioners regarding the management of multiple diseases, including socially significant ones (malignant… read more here.
Keywords: tissue microenvironment; mast cells; hydrogen; molecular hydrogen ... See more keywords