Articles with "tissue models" as a keyword



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Integration of Graphene Electrodes with 3D Skeletal Muscle Tissue Models.

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Published in 2020 at "Advanced healthcare materials"

DOI: 10.1002/adhm.201901137

Abstract: Integration of conductive electrodes with 3D tissue models can have great potential for applications in bioelectronics, drug screening, and implantable devices. As conventional electrodes cannot be easily integrated on 3D, polymeric, and biocompatible substrates, alternatives… read more here.

Keywords: skeletal muscle; integration; graphene; tissue models ... See more keywords
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3D Microvascularized Tissue Models by Laser‐Based Cavitation Molding of Collagen

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Published in 2022 at "Advanced Materials"

DOI: 10.1002/adma.202109823

Abstract: 3D tissue models recapitulating human physiology are important for fundamental biomedical research, and they hold promise to become a new tool in drug development. An integrated and defined microvasculature in 3D tissue models is necessary… read more here.

Keywords: microvascularized tissue; cavitation; collagen; models laser ... See more keywords
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Design of Perfused PTFE Vessel-Like Constructs for In Vitro Applications.

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Published in 2021 at "Macromolecular bioscience"

DOI: 10.1002/mabi.202100016

Abstract: Tissue models mimic the complex 3D structure of human tissues, which allows the study of pathologies and the development of new therapeutic strategies. The introduction of perfusion overcomes the diffusion limitation and enables the formation… read more here.

Keywords: like constructs; design perfused; vessel like; tissue models ... See more keywords
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Evaluating kurtosis‐based diffusion MRI tissue models for white matter with fiber ball imaging

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Published in 2017 at "NMR in Biomedicine"

DOI: 10.1002/nbm.3689

Abstract: In order to quantify well‐defined microstructural properties of brain tissue from diffusion MRI (dMRI) data, tissue models are typically employed that relate biological features, such as cell morphology and cell membrane permeability, to the diffusion… read more here.

Keywords: diffusion; tissue models; tissue; kurtosis ... See more keywords
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Mass Spectrometry Imaging of 3D Tissue Models

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Published in 2018 at "PROTEOMICS"

DOI: 10.1002/pmic.201700462

Abstract: A 3D cell culture is an artificially created environment in which cells are permitted to grow/interact with their surroundings in all three dimensions. Derived from 3D cell culture, organoids are generally small‐scale constructs of cells… read more here.

Keywords: methodology; mass spectrometry; tissue models; drug ... See more keywords
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Skin and Soft Tissue Models for Acinetobacter baumannii Infection.

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Published in 2019 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-9118-1_25

Abstract: Multidrug-resistant A. baumannii are important Gram-negative pathogens causing persistent wound infections in both wounded and burned victims, which often result in secondary complications such as delayed wound healing, skin graft failure, and sometimes more serious… read more here.

Keywords: models acinetobacter; skin soft; soft tissue; tissue models ... See more keywords
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Topology-Based Prediction of Pathway Dysregulation Induced by Intense Terahertz Pulses in Human Skin Tissue Models

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Published in 2018 at "Journal of Infrared, Millimeter, and Terahertz Waves"

DOI: 10.1007/s10762-018-0512-4

Abstract: The strong interaction between terahertz (THz) radiation and biological systems has motivated the development of several biomedical technologies, including imaging and spectroscopy applications with promising potential for improved disease diagnosis. This interaction mechanism also implies… read more here.

Keywords: skin tissue; human skin; tissue models; topology ... See more keywords
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Abstract ID: 38 Investigating energy deposition in cellular targets using multiscale tissue models

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Published in 2017 at "Physica Medica"

DOI: 10.1016/j.ejmp.2017.09.018

Abstract: Purpose To investigate energy deposition in subcellular targets, quantify the microdosimetric spread in a population of cells, and determine how these results depend on details of multiscale Monte Carlo tissue models. Methods Multiscale tissue models… read more here.

Keywords: specific energy; energy; tissue models; energy deposition ... See more keywords
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Optogenetic Control of Human Induced Pluripotent Stem Cell-Derived Cardiac Tissue Models.

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Published in 2022 at "Journal of the American Heart Association"

DOI: 10.1161/jaha.121.021615

Abstract: Background Optogenetics, using light-sensitive proteins, emerged as a unique experimental paradigm to modulate cardiac excitability. We aimed to develop high-resolution optogenetic approaches to modulate electrical activity in 2- and 3-dimensional cardiac tissue models derived from… read more here.

Keywords: tissue models; derived cardiac; cell; tissue ... See more keywords
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Quantification of Drugs in Brain and Liver Mimetic Tissue Models Using Raman Spectroscopy

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Published in 2022 at "Applied Spectroscopy"

DOI: 10.1177/00037028221139494

Abstract: Quantitative analysis of drug delivery with in biological systems is an integral challenge in drug development. Analytical techniques are important for assessing both drug target delivery, target action, and drug toxicology. Using mimetic tissue models,… read more here.

Keywords: spectroscopy; brain; raman spectroscopy; drug ... See more keywords
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3D Bioprinting-Based Vascularized Tissue Models Mimicking Tissue-Specific Architecture and Pathophysiology for in vitro Studies

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Published in 2021 at "Frontiers in Bioengineering and Biotechnology"

DOI: 10.3389/fbioe.2021.685507

Abstract: A wide variety of experimental models including 2D cell cultures, model organisms, and 3D in vitro models have been developed to understand pathophysiological phenomena and assess the safety and efficacy of potential therapeutics. In this… read more here.

Keywords: vascularized tissue; bioprinting based; based vascularized; tissue models ... See more keywords