Embedded Coaxial Bioprinting of Vascularized Tissue Models for Drug Evaluation
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202520097
Abstract: Vascularized tissue models represent a pivotal approach for enhancing the accuracy of clinical drug prediction by recapitulating the in vivo microenvironment. However, replicating the structural complexity, functional integration, and long‐term stability inherent in native vascular… read more here.
Keywords: vascularized tissue; tissue models; drug; embedded coaxial ... See more keywords
Integration of Graphene Electrodes with 3D Skeletal Muscle Tissue Models.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201901137
Abstract: Integration of conductive electrodes with 3D tissue models can have great potential for applications in bioelectronics, drug screening, and implantable devices. As conventional electrodes cannot be easily integrated on 3D, polymeric, and biocompatible substrates, alternatives… read more here.
Keywords: skeletal muscle; integration; graphene; tissue models ... See more keywords
3D Microvascularized Tissue Models by Laser‐Based Cavitation Molding of Collagen
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202109823
Abstract: 3D tissue models recapitulating human physiology are important for fundamental biomedical research, and they hold promise to become a new tool in drug development. An integrated and defined microvasculature in 3D tissue models is necessary… read more here.
Keywords: microvascularized tissue; cavitation; collagen; models laser ... See more keywords
Design of Perfused PTFE Vessel-Like Constructs for In Vitro Applications.
Sign Up to like & getrecommendations! Published in 2021 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202100016
Abstract: Tissue models mimic the complex 3D structure of human tissues, which allows the study of pathologies and the development of new therapeutic strategies. The introduction of perfusion overcomes the diffusion limitation and enables the formation… read more here.
Keywords: like constructs; design perfused; vessel like; tissue models ... See more keywords
Evaluating kurtosis‐based diffusion MRI tissue models for white matter with fiber ball imaging
Sign Up to like & getrecommendations! Published in 2017 at "NMR in Biomedicine"
DOI: 10.1002/nbm.3689
Abstract: In order to quantify well‐defined microstructural properties of brain tissue from diffusion MRI (dMRI) data, tissue models are typically employed that relate biological features, such as cell morphology and cell membrane permeability, to the diffusion… read more here.
Keywords: diffusion; tissue models; tissue; kurtosis ... See more keywords
Mass Spectrometry Imaging of 3D Tissue Models
Sign Up to like & getrecommendations! Published in 2018 at "PROTEOMICS"
DOI: 10.1002/pmic.201700462
Abstract: A 3D cell culture is an artificially created environment in which cells are permitted to grow/interact with their surroundings in all three dimensions. Derived from 3D cell culture, organoids are generally small‐scale constructs of cells… read more here.
Keywords: methodology; mass spectrometry; tissue models; drug ... See more keywords
Skin and Soft Tissue Models for Acinetobacter baumannii Infection.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9118-1_25
Abstract: Multidrug-resistant A. baumannii are important Gram-negative pathogens causing persistent wound infections in both wounded and burned victims, which often result in secondary complications such as delayed wound healing, skin graft failure, and sometimes more serious… read more here.
Keywords: models acinetobacter; skin soft; soft tissue; tissue models ... See more keywords
Topology-Based Prediction of Pathway Dysregulation Induced by Intense Terahertz Pulses in Human Skin Tissue Models
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Infrared, Millimeter, and Terahertz Waves"
DOI: 10.1007/s10762-018-0512-4
Abstract: The strong interaction between terahertz (THz) radiation and biological systems has motivated the development of several biomedical technologies, including imaging and spectroscopy applications with promising potential for improved disease diagnosis. This interaction mechanism also implies… read more here.
Keywords: skin tissue; human skin; tissue models; topology ... See more keywords
Abstract ID: 38 Investigating energy deposition in cellular targets using multiscale tissue models
Sign Up to like & getrecommendations! Published in 2017 at "Physica Medica"
DOI: 10.1016/j.ejmp.2017.09.018
Abstract: Purpose To investigate energy deposition in subcellular targets, quantify the microdosimetric spread in a population of cells, and determine how these results depend on details of multiscale Monte Carlo tissue models. Methods Multiscale tissue models… read more here.
Keywords: specific energy; energy; tissue models; energy deposition ... See more keywords
Engineering hiPSC-derived tissue models for advanced amyloidosis research and therapy development
Sign Up to like & getrecommendations! Published in 2024 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehae666.3777
Abstract: Transthyretin (TTR) amyloid cardiomyopathy (ATTR-CM) is a life-threatening disease currently lacking an optimal therapy, stemming from the absence of representative models. Our work aims to stablish for the first time an all-human 3D model of… read more here.
Keywords: tissue models; engineering hipsc; hipsc derived; therapy ... See more keywords
Optogenetic Control of Human Induced Pluripotent Stem Cell-Derived Cardiac Tissue Models.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Heart Association"
DOI: 10.1161/jaha.121.021615
Abstract: Background Optogenetics, using light-sensitive proteins, emerged as a unique experimental paradigm to modulate cardiac excitability. We aimed to develop high-resolution optogenetic approaches to modulate electrical activity in 2- and 3-dimensional cardiac tissue models derived from… read more here.
Keywords: tissue models; derived cardiac; cell; tissue ... See more keywords