Distinguishing tissue origin of bovine gelatin in processed products using LC/MS technique in combination with chemometrics tools.
Sign Up to like & getrecommendations! Published in 2020 at "Food chemistry"
DOI: 10.1016/j.foodchem.2020.126302
Abstract: Gelatin, as a by-product of the meat industry, is extracted from bone and skin of mainly bovine and porcine origins. It is used widely in the food, drug, and cosmetic industries. Authenticity testing methods can… read more here.
Keywords: tissue origin; origin bovine; distinguishing tissue; gelatin ... See more keywords
Macrophages of different tissue origin exhibit distinct inflammatory responses to mycobacterial infection.
Sign Up to like & getrecommendations! Published in 2021 at "Immunology and cell biology"
DOI: 10.1111/imcb.12493
Abstract: Macrophages display marked plasticity with functions in both inflammation and tissue repair. Evidence demonstrates that this spectrum of macrophage phenotypes is influenced by their local microenvironment and tissue origin. However, in vitro macrophage experiments often… read more here.
Keywords: tissue origin; infection; tissue; mycobacterial infection ... See more keywords
Identification of Tumor Tissue of Origin with RNA-Seq Data and Using Gradient Boosting Strategy
Sign Up to like & getrecommendations! Published in 2021 at "BioMed Research International"
DOI: 10.1155/2021/6653793
Abstract: Background Cancer of unknown primary (CUP) is a type of malignant tumor, which is histologically diagnosed as a metastatic carcinoma while the tissue-of-origin cannot be identified. CUP accounts for roughly 5% of all cancers. Traditional… read more here.
Keywords: rna seq; tissue origin; gradient boosting; tumor ... See more keywords
Abstract 6551: HiTAIC: Hierarchical tumor artificial intelligence classifier traces tissue of origin and tumor type in primary and metastasized tumors using DNA methylation data
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-6551
Abstract: Background: Human cancers are heterogenous by their cell composition and origination site. Cancer metastasis generates the conundrum of the unknown origin of migrated tumor cells. Tracing tissue of origin and tumor type in primary and… read more here.
Keywords: tumor; tissue origin; dna methylation; tumor type ... See more keywords
A Neural Network Framework for Predicting the Tissue-of-Origin of 15 Common Cancer Types Based on RNA-Seq Data
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2020.00737
Abstract: Sequencing-based identification of tumor tissue-of-origin (TOO) is critical for patients with cancer of unknown primary lesions. Even if the TOO of a tumor can be diagnosed by clinicopathological observation, reevaluations by computational methods can help… read more here.
Keywords: cancer types; framework; tissue origin; cancer ... See more keywords
Identifying cancer tissue-of-origin by a novel machine learning method based on expression quantitative trait loci
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.946552
Abstract: Cancer of unknown primary (CUP) refers to cancer with primary lesion unidentifiable by regular pathological and clinical diagnostic methods. This kind of cancer is extremely difficult to treat, and patients with CUP usually have a… read more here.
Keywords: cup; expression quantitative; tissue origin; expression ... See more keywords
A molecular taxonomy of tumors independent of tissue-of-origin
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DOI: 10.7490/f1000research.1118501.1
Abstract: Abstract Cancer is a complex disease involving disrupted cellular metabolism, basic biochemical processes, and the microenvironment. However, despite some generally agreed upon unifying principles (Hanahan and Weinberg 2000, 2011), molecular signatures remain largely indistinguishable from… read more here.
Keywords: tissue origin; tissue specific; biology; tissue ... See more keywords