Tissue plasminogen activator vs heparin for locking central venous catheters between apheresis procedures
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Apheresis"
DOI: 10.1002/jca.21697
Abstract: Central venous catheters (CVCs) for apheresis procedures require regular locking/flushes to maintain adequate flow rates. Literature comparing locking solutions for apheresis, where the time interval between procedures can be longer than for hemodialysis (many days… read more here.
Keywords: apheresis procedures; venous catheters; central venous; apheresis ... See more keywords
Detection of Protein Uptake in In Vitro Cultured Astrocytes Exemplified by the Uptake of the Serine Protease, Tissue Plasminogen Activator.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9068-9_14
Abstract: Astrocytes are heterogeneous cells of the central nervous system whose uptake of neurotransmitters and neuromodulators can influence synaptic signaling. Any malfunction in this process can lead to serious defects in synaptic transmission found in, for… read more here.
Keywords: serine protease; cultured astrocytes; vitro cultured; plasminogen activator ... See more keywords
Ischemia–Reperfusion Injury of Sciatic Nerve in Rats: Protective Role of Combination of Vitamin C with E and Tissue Plasminogen Activator
Sign Up to like & getrecommendations! Published in 2018 at "Neurochemical Research"
DOI: 10.1007/s11064-017-2465-8
Abstract: An ischemia/reperfusion injury of rat’s sciatic nerve was experimentally developed. In this model, we measured the in vivo production of superoxide radical, as a marker of oxidative stress and the occludin expression as an indicator… read more here.
Keywords: reperfusion; tissue plasminogen; ischemia; ischemia reperfusion ... See more keywords
Recombinant Tissue Plasminogen Activator-conjugated Nanoparticles Effectively Targets Thrombolysis in a Rat Model of Middle Cerebral Artery Occlusion
Sign Up to like & getrecommendations! Published in 2018 at "Current Medical Science"
DOI: 10.1007/s11596-018-1896-z
Abstract: SummaryThe efficacy and safety of recombinant tissue plasminogen activator (rtPA) need to be improved due to its low bioavailability and requirement of large dose administration. The purpose of this study was to develop a fibrin-targeted… read more here.
Keywords: plasminogen activator; tissue plasminogen; recombinant tissue; rtpa ... See more keywords
Diabetes Worsens Functional Outcomes in Young Female Rats: Comparison of Stroke Models, Tissue Plasminogen Activator Effects, and Sexes
Sign Up to like & getrecommendations! Published in 2017 at "Translational Stroke Research"
DOI: 10.1007/s12975-017-0525-7
Abstract: Diabetes worsens stroke outcome and increases the risk of hemorrhagic transformation (HT) after ischemic stroke, especially with tissue plasminogen activator (tPA) treatment. The widespread use of tPA is still limited by the fear of hemorrhagic… read more here.
Keywords: tpa; diabetes worsens; plasminogen activator; tissue plasminogen ... See more keywords
ENDOBRONCHIAL TISSUE PLASMINOGEN ACTIVATOR (TPA) ADMINISTRATION TO RESOLVE ENDOBRONCHIAL OBSTRUCTION DUE TO SIGNIFICANT BLOOD CLOT BURDEN IN A SAR COV 2 POSITIVE PATIENT ON EXTRACORPOREAL MEMBRANE OXYGENATION (ECMO)
Sign Up to like & getrecommendations! Published in 2021 at "Chest"
DOI: 10.1016/j.chest.2021.07.641
Abstract: TOPIC: Critical Care TYPE: Fellow Case Reports INTRODUCTION: Endobronchial obstruction can be a potentially life-threatening condition leading to respiratory failure. A significant cause includes endobronchial blood clots. The presence of blood clots in a patient… read more here.
Keywords: clot; clot burden; blood; tissue plasminogen ... See more keywords
Viscoelastic Tissue Plasminogen Activator Challenge Predicts Massive Transfusion in 15 Minutes.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American College of Surgeons"
DOI: 10.1016/j.jamcollsurg.2017.02.018
Abstract: BACKGROUND Coagulopathy is associated with massive transfusion in trauma, yet most clinical scores to predict this end point do not incorporate coagulation assays. Previous work has identified that shock increases circulating tissue plasminogen activator (tPA).… read more here.
Keywords: tpa; teg; trauma; transfusion ... See more keywords
Preparation of thermosensitive magnetic liposome encapsulated recombinant tissue plasminogen activator for targeted thrombolysis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Magnetism and Magnetic Materials"
DOI: 10.1016/j.jmmm.2016.10.122
Abstract: Abstract Recombinant tissue plasminogen activator (rtPA) was encapsulated in thermosensitive magnetic liposome (TML) prepared from 1,2-dipalmitoyl- sn -glycero-3-phosphocholine, distearolyphosphatidyl ethanolamine- N -poly(ethylene glycol) 2000, cholesterol and Fe 3 O 4 magnetic nanoparticles by solvent evaporation/sonication… read more here.
Keywords: magnetic liposome; drug; thermosensitive magnetic; recombinant tissue ... See more keywords
Intravenous thrombolysis with tissue-plasminogen activator in small vessel occlusion
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Neuroscience"
DOI: 10.1016/j.jocn.2019.03.036
Abstract: Intravenous tissue-plasminogen activator (IV-TPA) treatment in acute ischemic stroke (AIS) patients due to small vessel occlusion (SVO) has been debated because of its small expected benefit and symptomatic intracranial hemorrhage (SICH) risk. Furthermore, data on… read more here.
Keywords: plasminogen activator; tissue plasminogen; small vessel; vessel occlusion ... See more keywords
Use of recombinant tissue plasminogen activator for treatment of recalcitrant anterior uveitis: A case series
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Taibah University Medical Sciences"
DOI: 10.1016/j.jtumed.2018.03.005
Abstract: Management of inflammation after surgery for recalcitrant anterior uveitis is challenging. Herein, we report successful treatment using intracameral injection of recombinant tissue plasminogen activator (rtPA) in two patients with recalcitrant anterior uveitis, due to infective… read more here.
Keywords: anterior uveitis; inflammation; recalcitrant anterior; recombinant tissue ... See more keywords
Controversies in cerebrovascular disease: high or low doses of recombinant tissue plasminogen activator to treat acute stroke? A literature review
Sign Up to like & getrecommendations! Published in 2020 at "Neurologia"
DOI: 10.1016/j.nrleng.2018.04.002
Abstract: Abstract Introduction The use of low doses of recombinant tissue plasminogen activator (rt-PA) was initially proposed in Asian countries in response to racial peculiarities related to the functionality of fibrinogen and coagulation factors that potentially… read more here.
Keywords: use; doses recombinant; acute stroke; recombinant tissue ... See more keywords