Exome copy number variation detection: Use of a pool of unrelated healthy tissue as reference sample
Sign Up to like & getrecommendations! Published in 2017 at "Genetic Epidemiology"
DOI: 10.1002/gepi.22019
Abstract: An increasing number of bioinformatic tools designed to detect CNVs (copy number variants) in tumor samples based on paired exome data where a matched healthy tissue constitutes the reference have been published in the recent… read more here.
Keywords: tissue reference; pool; unrelated healthy; reference ... See more keywords
Validation of a Simplified Tissue-to-Reference Ratio Measurement Using SUVR to Assess Synaptic Density Alterations in Alzheimer Disease with [11C]UCB-J PET
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Nuclear Medicine"
DOI: 10.2967/jnumed.124.267419
Abstract: Visual Abstract Simplified methods of acquisition and quantification would facilitate the use of synaptic density imaging in multicenter and longitudinal studies of Alzheimer disease (AD). We validated a simplified tissue-to-reference ratio method using SUV ratios… read more here.
Keywords: tissue reference; simplified tissue; synaptic density; density ... See more keywords