Label‐free analysis of inflammatory tissue remodeling in murine lung tissue based on multiphoton microscopy, Raman spectroscopy and machine learning
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biophotonics"
DOI: 10.1002/jbio.202200073
Abstract: Inflammatory fibrotic tissue remodeling can lead to severe morbidity. Histopathology grading requires extraction of biopsies and elaborate tissue processing. Label‐free optical technologies can provide diagnostic readout without preparation and artificial stainings and show potential for… read more here.
Keywords: label free; spectroscopy; microscopy; tissue remodeling ... See more keywords
Biostimulatory Micro-Fragmented Nanofiber-Hydrogel Composite Improves Mesenchymal Stem Cell Delivery and Soft Tissue Remodeling.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202202309
Abstract: Functional microgels are preferred stem cell carriers due to the ease of delivery through minimally invasive injection and seamless integration with the surrounding host tissue. A biostimulatory nanofiber-hydrogel composite (NHC) has been previously developed through… read more here.
Keywords: cell; stem cell; soft tissue; tissue remodeling ... See more keywords
Exosomes as a storehouse of tissue remodeling proteases and mediators of cancer progression
Sign Up to like & getrecommendations! Published in 2019 at "Cancer and Metastasis Reviews"
DOI: 10.1007/s10555-019-09813-5
Abstract: Rapidly increasing scientific reports of exosomes and their biological effects have improved our understanding of their cellular sources and their cell-to-cell communication. These nano-sized vesicles act as potent carriers of regulatory bio-macromolecules and can induce… read more here.
Keywords: tissue remodeling; remodeling proteases; exosomes storehouse; tissue ... See more keywords
Urinary biomarkers of inflammation and tissue remodeling may predict bladder dysfunction in patients with benign prostatic hyperplasia
Sign Up to like & getrecommendations! Published in 2020 at "International Urology and Nephrology"
DOI: 10.1007/s11255-020-02537-4
Abstract: Purpose To evaluate the expression of urinary biomarkers of inflammation and tissue remodeling in patients with BPH undergoing surgery and evaluate the association of biomarkers with postoperative urodynamic outcomes Materials and methods We analyzed urine… read more here.
Keywords: tissue remodeling; biomarkers inflammation; remodeling may; inflammation tissue ... See more keywords
Ageing mechanisms that contribute to tissue remodeling in lung disease
Sign Up to like & getrecommendations! Published in 2021 at "Ageing Research Reviews"
DOI: 10.1016/j.arr.2021.101405
Abstract: Age is a major risk factor for chronic respiratory diseases such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD) and certain phenotypes of asthma. The recent COVID-19 pandemic also highlights the increased susceptibility… read more here.
Keywords: remodeling lung; tissue remodeling; ageing mechanisms; disease ... See more keywords
A CLUSTER ANALYSIS OF BRONCHIECTASIS PATIENTS BASED ON THE AIRWAY IMMUNE PROFILE.
Sign Up to like & getrecommendations! Published in 2020 at "Chest"
DOI: 10.1016/j.chest.2020.11.011
Abstract: BACKGROUND Clinical heterogeneity in bronchiectasis remains a challenge to improve the appropriate targeting of therapies and patient management. Antimicrobial peptides (AMPs) have been linked to disease severity and phenotype. RESEARCH QUESTION Can we identify clusters… read more here.
Keywords: patients based; tissue remodeling; bronchiectasis; remodeling damage ... See more keywords
Tissue remodeling after ocular surface reconstruction with denuded amniotic membrane
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-24694-4
Abstract: Amniotic membrane (AM) has been widely used as a temporary or permanent graft in the treatment of various ocular surface diseases. In this study, we compared the epithelial wound healing and tissue remodeling after ocular… read more here.
Keywords: reconstruction; tissue remodeling; ocular surface; amniotic membrane ... See more keywords
Toll-Like Receptor-4 Disruption Suppresses Adipose Tissue Remodeling and Increases Survival in Cancer Cachexia Syndrome
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-36626-3
Abstract: Cancer-induced cachexia, characterized by systemic inflammation, body weight loss, adipose tissue (AT) remodeling and muscle wasting, is a malignant metabolic syndrome with undefined etiology. Here, we show that both genetic ablation and pharmacological inhibition of… read more here.
Keywords: tissue remodeling; cachexia; tlr4; adipose tissue ... See more keywords
MRCK: a master regulator of tissue remodeling or another ‘ROCK’ in the epithelial block?
Sign Up to like & getrecommendations! Published in 2021 at "Tissue Barriers"
DOI: 10.1080/21688370.2021.1916380
Abstract: ABSTRACT The epithelium forms a smart barrier to the external environment that can remodel whilst maintaining tissue integrity, a feature important for development, homeostasis, and function. Its dysregulation can lead to diseases ranging from cancer… read more here.
Keywords: tissue remodeling; remodeling another; mrck master; tissue ... See more keywords
The Role of Proprotein Convertases in Upper Airway Remodeling
Sign Up to like & getrecommendations! Published in 2022 at "Molecules and Cells"
DOI: 10.14348/molcells.2022.0019
Abstract: Chronic rhinosinusitis (CRS) is a multifactorial, heterogeneous disease characterized by persistent inflammation of the sinonasal mucosa and tissue remodeling, which can include basal/progenitor cell hyperplasia, goblet cell hyperplasia, squamous cell metaplasia, loss or dysfunction of… read more here.
Keywords: cell; proprotein convertases; tissue remodeling; role proprotein ... See more keywords
Controlling Mesenchyme Tissue Remodeling via Spatial Arrangement of Mechanical Constraints
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.833595
Abstract: Tissue morphogenetic remodeling plays an important role in tissue repair and homeostasis and is often governed by mechanical stresses. In this study, we integrated an in vitro mesenchymal tissue experimental model with a volumetric contraction-based… read more here.
Keywords: mesenchyme tissue; controlling mesenchyme; tissue remodeling; mechanical constraints ... See more keywords