Increasing tissue requirements in lymphoma trials may exclude patients with high-risk disease or worse prognosis
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DOI: 10.1182/bloodadvances.2022007569
Abstract: Key Points • Patients who underwent core needle biopsy are more likely to have poor-risk disease features and inadequate tissue for molecular analyses.• Increasing tissue requirements of biomarker-driven trials may exclude patients with high-risk DLBCL… read more here.
Keywords: increasing tissue; trials may; risk; risk disease ... See more keywords
Identification of C. elegans ASNA-1 domains and tissue requirements that differentially influence platinum sensitivity and growth control
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DOI: 10.1371/journal.pgen.1010538
Abstract: ASNA1 plays an essential role in cisplatin chemotherapy response, type 2 diabetes, and heart disease. It is also an important biomarker in the treatment response of many diseases. Biochemically, ASNA1 has two mutually exclusive redox-modulated… read more here.
Keywords: function; sensitivity; elegans asna; response ... See more keywords