Intestinal CD8+ tissue‐resident memory T cells: From generation to function
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202149759
Abstract: Tissue‐resident memory T cells (Trm), and particularly the CD8+ subset, have been shown to play a pivotal role in protection against infections and tumors. Studies in animal models and human tissues have highlighted that, while… read more here.
Keywords: resident memory; tissue resident; memory cells; intestinal cd8 ... See more keywords
Tissue-resident memory T (TRM ) cells: front-line workers of the immune system.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of immunology"
DOI: 10.1002/eji.202250060
Abstract: Tissue-resident memory T (TRM ) cells play a vital role in local immune protection against infection and cancer. The location of TRM cells within peripheral tissues at sites of pathogen invasion allows for the rapid… read more here.
Keywords: resident memory; tissue resident; memory trm; trm cells ... See more keywords
Isolation and Purification of Tissue Resident Macrophages for the Analysis of Nuclear Receptor Activity.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9130-3_5
Abstract: Tissue resident macrophages (TRMs) are multifunctional immune cells present in all tissues, contributing to the correct development, homeostasis, and protection against pathogens and injury. TRMs are morphologically and functionally heterogeneous, as a result of both… read more here.
Keywords: tissue resident; tissue; nuclear receptor; receptor activity ... See more keywords
Pathogenic role of tissue-resident memory T cells in autoimmune diseases.
Sign Up to like & getrecommendations! Published in 2018 at "Autoimmunity reviews"
DOI: 10.1016/j.autrev.2018.03.014
Abstract: The tissue-resident memory T (TRM) cells constitute a newly identified subset of memory T cells which are non-circulating and they persist for long-term in epithelial barrier tissues, including skin, lung, gastrointestinal tract and reproductive tract,… read more here.
Keywords: memory cells; autoimmune diseases; tissue resident; trm cells ... See more keywords
ILC1 Confer Early Host Protection at Initial Sites of Viral Infection
Sign Up to like & getrecommendations! Published in 2017 at "Cell"
DOI: 10.1016/j.cell.2017.09.052
Abstract: Infection is restrained by the concerted activation of tissue-resident and circulating immune cells. Whether tissue-resident lymphocytes confer early antiviral immunity at local sites of primary infection prior to the initiation of circulating responses is not well… read more here.
Keywords: confer early; viral infection; infection; tissue resident ... See more keywords
Generating tissue-resident macrophages from pluripotent stem cells: Lessons learned from microglia.
Sign Up to like & getrecommendations! Published in 2018 at "Cellular immunology"
DOI: 10.1016/j.cellimm.2018.01.019
Abstract: Over the past decades, the importance of the immune system in a broad scope of pathologies, has drawn attention towards tissue-resident macrophages, such as microglia in the brain. To enable the study of for instance… read more here.
Keywords: macrophages pluripotent; resident macrophages; stem cells; tissue resident ... See more keywords
Organ-Specific Fate, Recruitment, and Refilling Dynamics of Tissue-Resident Macrophages during Blood-Stage Malaria.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.11.059
Abstract: Inflammation-induced disappearance of tissue-resident macrophages represents a key pathogen defense mechanism. Using a model of systemic blood-stage malaria, we studied the dynamics of tissue-resident macrophages in multiple organs to determine how they are depleted and… read more here.
Keywords: stage malaria; tissue resident; tissue; blood stage ... See more keywords
Dynamic changes to tissue-resident immunity after MHC-matched and MHC-mismatched solid organ transplantation.
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.109141
Abstract: The heterogeneous pool of tissue-resident lymphocytes in solid organs mediates infection responses and supports tissue integrity and repair. Their vital functions in normal physiology suggest an important role in solid organ transplantation; however, their detailed… read more here.
Keywords: mhc matched; solid organ; organ transplantation; mhc mismatched ... See more keywords
Tissue resident cell processes determine organ damage in systemic lupus erythematosus.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical immunology"
DOI: 10.1016/j.clim.2021.108919
Abstract: Systemic lupus erythematosus (SLE) is an autoimmune disease that affects almost any organ. Multiple immunological abnormalities involving every domain of the immune system contribute to the expression of the disease. It is now recognized that… read more here.
Keywords: damage; systemic lupus; tissue resident; lupus erythematosus ... See more keywords
Tissue resident memory T cells and viral immunity.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in virology"
DOI: 10.1016/j.coviro.2016.11.011
Abstract: Tissue resident memory T cells (TRM) constitute a recently identified T cell lineage that is responsible for frontline defense against viral infections. In contrast to central and effector memory T cells, which constitutively recirculate between… read more here.
Keywords: cells viral; memory cells; tissue resident; tissue ... See more keywords
Heterogeneity of Tissue Resident Memory T cells.
Sign Up to like & getrecommendations! Published in 2022 at "Immunology letters"
DOI: 10.1016/j.imlet.2022.02.009
Abstract: Non-lymphoid organs, in mice and humans, contain CD8+ tissue-resident memory T (TRM) cells. They play important roles in tissue homeostasis as well as defence against infections and cancer. TRM cells have common characteristics that enables… read more here.
Keywords: trm cells; tissue; resident memory; tissue resident ... See more keywords