Adipose Tissue‐Resident Sphingomonas Paucimobilis Suppresses Adaptive Thermogenesis by Reducing 15‐HETE Production and Inhibiting AMPK Pathway
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202310236
Abstract: Obesity represents a low‐grade chronic inflammation status, which is associated with compromised adaptive thermogenesis. However, the mechanisms underlying the defective activation of thermogenesis in chronic inflammation remain unclear. Here, a chronic inflammatory model is first… read more here.
Keywords: thermogenesis; tissue resident; sphingomonas paucimobilis; adipose tissue ... See more keywords
Tissue‐Resident Myeloid and Histiocytic Cells in Health and Disease: Novel Emerging Concepts
Sign Up to like & getrecommendations! Published in 2025 at "American Journal of Hematology"
DOI: 10.1002/ajh.70062
Abstract: Although all myeloid cells are considered to derive from hematopoietic stem cells, the cells in each myeloid lineage are heterogeneous populations, and their distribution and functions vary, depending on underlying physiologic and pathologic processes, age,… read more here.
Keywords: disease; resident myeloid; myeloid; tissue resident ... See more keywords
Intestinal CD8+ tissue‐resident memory T cells: From generation to function
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202149759
Abstract: Tissue‐resident memory T cells (Trm), and particularly the CD8+ subset, have been shown to play a pivotal role in protection against infections and tumors. Studies in animal models and human tissues have highlighted that, while… read more here.
Keywords: resident memory; tissue resident; memory cells; intestinal cd8 ... See more keywords
Tissue-resident memory T (TRM ) cells: front-line workers of the immune system.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of immunology"
DOI: 10.1002/eji.202250060
Abstract: Tissue-resident memory T (TRM ) cells play a vital role in local immune protection against infection and cancer. The location of TRM cells within peripheral tissues at sites of pathogen invasion allows for the rapid… read more here.
Keywords: resident memory; tissue resident; memory trm; trm cells ... See more keywords
Tissue‐resident memory T cells in immunotherapy and immune‐related adverse events by immune checkpoint inhibitor
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Cancer"
DOI: 10.1002/ijc.34940
Abstract: Tissue‐resident memory T cells (TRM) are a specialized subset of T cells that reside in tissues and provide long‐term protective immunity against pathogens that enter the body through that specific tissue. TRM cells have specific… read more here.
Keywords: immune checkpoint; checkpoint inhibitor; tissue resident;
Isolation and Purification of Tissue Resident Macrophages for the Analysis of Nuclear Receptor Activity.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9130-3_5
Abstract: Tissue resident macrophages (TRMs) are multifunctional immune cells present in all tissues, contributing to the correct development, homeostasis, and protection against pathogens and injury. TRMs are morphologically and functionally heterogeneous, as a result of both… read more here.
Keywords: tissue resident; tissue; nuclear receptor; receptor activity ... See more keywords
Pathogenic role of tissue-resident memory T cells in autoimmune diseases.
Sign Up to like & getrecommendations! Published in 2018 at "Autoimmunity reviews"
DOI: 10.1016/j.autrev.2018.03.014
Abstract: The tissue-resident memory T (TRM) cells constitute a newly identified subset of memory T cells which are non-circulating and they persist for long-term in epithelial barrier tissues, including skin, lung, gastrointestinal tract and reproductive tract,… read more here.
Keywords: memory cells; autoimmune diseases; tissue resident; trm cells ... See more keywords
ILC1 Confer Early Host Protection at Initial Sites of Viral Infection
Sign Up to like & getrecommendations! Published in 2017 at "Cell"
DOI: 10.1016/j.cell.2017.09.052
Abstract: Infection is restrained by the concerted activation of tissue-resident and circulating immune cells. Whether tissue-resident lymphocytes confer early antiviral immunity at local sites of primary infection prior to the initiation of circulating responses is not well… read more here.
Keywords: confer early; viral infection; infection; tissue resident ... See more keywords
Generating tissue-resident macrophages from pluripotent stem cells: Lessons learned from microglia.
Sign Up to like & getrecommendations! Published in 2018 at "Cellular immunology"
DOI: 10.1016/j.cellimm.2018.01.019
Abstract: Over the past decades, the importance of the immune system in a broad scope of pathologies, has drawn attention towards tissue-resident macrophages, such as microglia in the brain. To enable the study of for instance… read more here.
Keywords: macrophages pluripotent; resident macrophages; stem cells; tissue resident ... See more keywords
Organ-Specific Fate, Recruitment, and Refilling Dynamics of Tissue-Resident Macrophages during Blood-Stage Malaria.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.11.059
Abstract: Inflammation-induced disappearance of tissue-resident macrophages represents a key pathogen defense mechanism. Using a model of systemic blood-stage malaria, we studied the dynamics of tissue-resident macrophages in multiple organs to determine how they are depleted and… read more here.
Keywords: stage malaria; tissue resident; tissue; blood stage ... See more keywords
Dynamic changes to tissue-resident immunity after MHC-matched and MHC-mismatched solid organ transplantation.
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.109141
Abstract: The heterogeneous pool of tissue-resident lymphocytes in solid organs mediates infection responses and supports tissue integrity and repair. Their vital functions in normal physiology suggest an important role in solid organ transplantation; however, their detailed… read more here.
Keywords: mhc matched; solid organ; organ transplantation; mhc mismatched ... See more keywords